Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery
- PMID: 21728738
- PMCID: PMC4148070
- DOI: 10.3109/14767058.2011.587559
Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery
Abstract
We prospectively identified 96 women consuming at least 4 drinks/day during pregnancy by screening 9628 pregnant women. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; 98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery.
References
-
- Albertsen K, Andersen AM, Olsen J, Grønbaek M. Alcohol consumption during pregnancy and the risk of preterm delivery. Am J Epidemiol. 2004;159:155–161. - PubMed
-
- Kesmodel U, Wisborg K, Olsen SF, Henriksen TB, Secher NJ. Moderate alcohol intake during pregnancy and the risk of stillbirth and death in the first year of life. Am J Epidemiol. 2002;155:305–312. - PubMed
-
- Sokol RJ, Janisse JJ, Louis JM, Bailey BN, Ager J, Jacobson SW, Jacobson JL. Extreme prematurity: an alcohol-related birth effect. Alcohol Clin Exp Res. 2007;31:1031–1037. - PubMed
-
- Strandberg-Larsen K, Nielsen NR, Grønbaek M, Andersen PK, Olsen J, Andersen AM. Binge drinking in pregnancy and risk of fetal death. Obstet Gynecol. 2008;111:602–609. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical