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. 1990 Nov;87(21):8360-4.
doi: 10.1073/pnas.87.21.8360.

Host genes that influence transposition in yeast: the abundance of a rare tRNA regulates Ty1 transposition frequency

H Xu  1 , J D Boeke
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Host genes that influence transposition in yeast: the abundance of a rare tRNA regulates Ty1 transposition frequency

H Xu et al. Proc Natl Acad Sci U S A. 1990 Nov.

Erratum in

  • Proc Natl Acad Sci U S A 1991 Mar 15;88(6):2612

Abstract

Genetic screening of a yeast genomic library in a high-copy-number vector identified the normally single copy tRNA(CCU Arg) gene as one of the genes and reduces Ty1 transposition frequency when overexpressed. Immunoblot analyses of Ty1-encoded proteins indicate an inverse correlation between the copy number of the tRNA gene and the production of the TYB protein. Thus, Ty1 transposition frequency is apparently regulated by the level of tRNA(CCU Arg) in yeast cells.

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References

    1. Mol Cell Biol. 1990 Jun;10(6):2695-702 - PubMed
    1. Gene. 1987;59(1):1-18 - PubMed
    1. Yeast. 1986 Sep;2(3):163-7 - PubMed
    1. Mol Gen Genet. 1987 May;207(2-3):421-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 May;82(9):2829-33 - PubMed

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