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Case Reports
. 2011 Jan;15(1):56-9.
doi: 10.4103/0973-029X.80027.

Bilateral maxillary brown tumors in a patient with primary hyperparathyroidism: Report of a rare entity and review of literature

Affiliations
Case Reports

Bilateral maxillary brown tumors in a patient with primary hyperparathyroidism: Report of a rare entity and review of literature

N Soundarya et al. J Oral Maxillofac Pathol. 2011 Jan.

Abstract

Brown tumors are erosive bony lesions caused by rapid osteoclastic activity and peritrabecular fibrosis due to hyperparathyroidism, resulting in a local destructive phenomenon. The classical "brown tumor" is commonly seen in ends of long bones, the pelvis and ribs. Facial involvement is rare and, when present, usually involves the mandible. We report a case of 60-year-old male with a rare initial presentation of primary hyperparathyroidism with bilateral maxillary brown tumors. The present case represents the third report of the bilateral maxillary brown tumors in a patient with primary hyperparathyroidism. Differential diagnosis is important for the right treatment choice. It should exclude other giant cell lesions that affect the maxillae.

Keywords: Brown tumor; hyperparathyroidism; maxilla.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
A diffuse swelling in the left infra-orbital and zygomatic region
Figure 2
Figure 2
Swelling on the right index finger
Figure 3
Figure 3
Swelling of the alveolar ridge on the right maxilla extending up to the midline of the palate
Figure 4
Figure 4
Swelling was present on the left maxillary sulcus in relation to 24, 25, 26
Figure 5
Figure 5
Multinucleated giant cells scattered in cellular fibroblastic tissue background (H and E, 40×)

References

    1. Gnepp DR. Diagnostic Surgical pathology of the head and neck. 2nd ed. Philadelphia: W B Saunders Co; 1997. p. 781.
    1. Krause I, Eisenstein B, Davidovits M, Cleper R, Tobar A, Calderon S. Maxillomandibular brown tumor –a rare complication of chronic renal failure. Pediatr Nephrol. 2000;14:499–501. - PubMed
    1. Jebasingh F, Jacob JJ, Shah A, Paul TV, Seshadri MS. Bilateral maxillary brown tumors as the first presentation of primary hyperparathyroidism. Oral Maxillofac Surg. 2008;12:97–100. - PubMed
    1. Auclair PL, Avendt DM, Hellstein JW. Giant cell lesions of the jaws. Oral Maxillofac Surg Clin North Am. 1997;9:655–80.
    1. Neville BW, Damm DD, Allen CM, Bouquot JE. 2nd ed. Pennsylvania: Saunders; 2002. Oral and Maxillofacial Pathology; pp. 724–6.

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