Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jan;12(1):7-11.
doi: 10.4103/1995-705X.81550.

Coronary Artery Disease in Patients Aged 35 or less - A Different Beast?

T Christus  1 , A M Shukkur, I Rashdan, T Koshy, M Alanbaei, M Zubaid, N Hayat, A Alsayegh
Affiliations

Coronary Artery Disease in Patients Aged 35 or less - A Different Beast?

T Christus et al. Heart Views. 2011 Jan.

Abstract

Aim: To assess the extent and severity of coronary artery disease (CAD) in 200 consecutive patients aged 35 years or less undergoing diagnostic coronary angiography.

Patients and methods: Findings in these 200 patients (≤ 35 years of age) were analyzed to find the extent and severity of CAD. The mean age was 31.69 (±3.76) years. Majority were males (94%) and from the Arab ethnicity (70.5%).

Result: Smoking (71%) and history of premature CAD (27%) were the most frequent risk factors (RF). History of previous ST elevation myocardial infarction (MI) was present in 68%. Anterior wall MI was the most frequent location (63.3%). The majority (54.3%) had moderate or large size MI. Ejection fraction (EF) less than 50% was noted in 30.3%. Left main or triple vessel CAD was seen in 15%. One- and two-vessel CAD was seen in 32.5% and 19% patients, respectively. Coronary angiogram was completely normal in 23.5%. The majority (54.5%) were treated conservatively and the rest (45.5%) needed percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG). The mean number of stents used was 1.3 ± 0.67 and the mean length of stents used was 20.3 ± 12.6 mm.

Conclusion: The extent and severity of CAD was very significant in this subgroup of very young (≤35 years) Asian patients. Smoking was the main risk factor and half of the patients needed either PCI or CABG.

Keywords: Coronary artery disease; ethinicity; premature coronary artery disease; young patients.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Fournier JA, Sanches A, Quero J, Perez Cortacero JA, Gonzales BA. Myocardial infarction in men aged 40 years or less: prospective clinical – angiographic study. Clin Cardiol. 1996;19:631–6. - PubMed
    1. Cole JH, Sperling LS. Premature Coronary artery disease: Clinical risk factors and prognosis. Curr Atheroscler Rep. 2004;6:121–5. - PubMed
    1. Imazio M, Bobbio M, Bergerone S, Barlera S, Maggioni AP. Clinical and epidemiological characteristics of juvenile myocardial infarction in Italy: The GISSI experience. G Ital Cardiol. 1998;28:505–12. - PubMed
    1. Wolfe AM, Vacek JL. Myocardial Infarction in the young. Chest. 1988;94:926–30. - PubMed
    1. Doughty M, Mehta R, Bruckman D, Das S, Karavite D, Tsai T, et al. Acute myocardial infarction in the young - The University of Michigan experience. Am Heart J. 2002;143:56–62. - PubMed