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. 2011 Sep;32(5):406-10.
doi: 10.1007/s00292-011-1452-0.

[Rabies transmission through organ transplantation]

[Article in German]
P Wohlsein  1 , W Baumgärtner, H H Kreipe, A Haverich, A Hori, A C Stan
Affiliations

[Rabies transmission through organ transplantation]

[Article in German]
P Wohlsein et al. Pathologe. 2011 Sep.

Abstract

Classic rabies is a progressive and lethal infectious disease of animals, which may be transmitted to humans. Inter-human infections are extremely rare. The present case describes transmittal of rabies virus by lung transplantation from an infected donor. Histologically, a lymphocytic encephalomyelitis with neuronal cytoplasmic inclusion bodies was found. Immunohistochemically, rabies virus antigen was detected in the central, autonomous and peripheral nervous system. By means of electron microscopy, virions were demonstrated in the brain. A central task of health care in transplantations is the detection of uncommon infectious agents and the prevention of their transmittal.

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