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Meta-Analysis
. 2011 Jul 6;2011(7):CD006224.
doi: 10.1002/14651858.CD006224.pub3.

Chinese herbal medicine in the treatment of ectopic pregnancy

Hai Bo Qu  1 , Wang Dengfeng, Taixiang Wu, Jane Marjoribanks, Sun Ying, Jia Haijun, Jing Zhang, Lina Hu
Affiliations
Meta-Analysis

Chinese herbal medicine in the treatment of ectopic pregnancy

Hai Bo Qu et al. Cochrane Database Syst Rev. .

Abstract

Background: Traditionally Chinese herbal medicine (CHM) has been used widely in Chinese hospitals to treat ectopic pregnancy. Many studies have been published supporting its use but the evidence has not been systematically reviewed. This is and update of the review published in 2007.

Objectives: To determine the effectiveness and safety of CHM in the treatment of ectopic pregnancy.

Search strategy: Computerised databases (CENTRAL (The Cochrane Library), MEDLINE, EMBASE, Chinese Biomedical Database, China National Knowledge Infrastructure, VIP, Traditional Chinese Medicine Database System) were searched from their inception to November 2010 for relevant trials.

Selection criteria: Randomised controlled trials (RCT) on the use of CHM for the treatment of ectopic pregnancy.

Data collection and analysis: Original authors of the identified studies were contacted to determine the trial design and identify authentic RCTs. Two review authors extracted and analysed the data.

Main results: The search identified 281 trials. Only two studies involving a total of 157 participants were confirmed to be authentic RCTs (Li 2004c; Zhao 2000). Both were of poor methodological quality with a high risk of conflicted interest and potential for bias in favour of the intervention. We could not reach a definitive conclusion from the results. The pooled result showed that adding a Western medicine to CHM resulted in a significantly higher treatment success rate than with CHM alone (RR 1.33, 95% CI 1.08 to 1.63). When CHM plus Western medicine was compared to CHM alone for the time to disappearance of abdominal pain, again the results favoured the arm that included Western medicine (RR -2.09, 95% CI -4.14 to -0.04). Results were inconsistent for the time required for human chorionic gonadotropin (beta-hCG) to return to normal. One study favoured CHM plus Western medicine over Western medicine (with or without placebo) (MD -6.68, 95% CI -11.49 to -1.87); when CHM plus Western medicine was compared to CHM alone the results favoured the arm that included Western medicine (MD -8.12, 95% CI -10.89 to -5.53).

Authors' conclusions: We have not found any well-designed trials investigating Chinese herbal medicines in the treatment of ectopic pregnancy. We cannot support or refute any CHM preparation for clinical use on the basis of evidence from randomised controlled trials.

PubMed Disclaimer

Conflict of interest statement

None known

Figures

1
1
2
2
Risk of bias graph: review authors' judgements about each risk of bias item presented as percentages across all included studies.
3
3
Risk of bias summary: review authors' judgements about each risk of bias item for each included study.
1.1
1.1. Analysis
Comparison 1 TCHM versus control, Outcome 1 Treatment success rate.
1.2
1.2. Analysis
Comparison 1 TCHM versus control, Outcome 2 Time to cessation of abdominal pain (days).
1.3
1.3. Analysis
Comparison 1 TCHM versus control, Outcome 3 Time to cessation of vaginal bleeding (days).
1.4
1.4. Analysis
Comparison 1 TCHM versus control, Outcome 4 Time for serum beta‐hCG levels to return to normal (days).
1.5
1.5. Analysis
Comparison 1 TCHM versus control, Outcome 5 Diminution of the ectopic pregnancy mass by ultrasound (mm).
1.6
1.6. Analysis
Comparison 1 TCHM versus control, Outcome 6 Duration of hospital stay (days).
1.7
1.7. Analysis
Comparison 1 TCHM versus control, Outcome 7 Adverse events rate.
See this image and copyright information in PMC

Update of

References

References to studies included in this review

Li 2004c {published data only}
    1. Li WL, Li DJ, Lu Y, Zhou J, Liu CL, Pan TH. The clinical observation of ectopic recipe combined with methotrexate in the treatment for 32 cases of ectopic pregnancy. Journal of Anhui TCM College 2004;23(2):19‐20.
Zhao 2000 {published data only}
    1. Zhao X, Huang GY. The comparison of three kinds of drug treatments for ectopic pregnancy. Chinese Journal of Practical Gynecology and Obstetrics 2000;16(4):221‐2.

References to studies excluded from this review

An 2003 {published data only}
    1. An FJ, Liu M, Xu H. The effect observation of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Medical Journal of Communication 2003;17(3):300‐1.
Bai 2010 {published data only}
    1. Bai XY, Dong YY. The clinical observation of methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for 96 cases of early ectopic pregnancy. Journal of Clinical and Experimental Medicine 2010;9(8):627‐9.
Bao 2007a {published data only}
    1. Bao LH. The clinical effect of traditional Chinese medicine conservative treatment for cured ectopic pregnancy. Acta Medicinae Sinica 2007;20(3):480‐1.
Bao 2007b {published data only}
    1. Bao LH. The clinical observation of traditional Chinese medicine treatment for fallopian tube recanalization of cured ectopic pregnancy. Yunnan Journal of Traditional Chinese Medicine and Materia Medica 2007;28(7):4‐5.
Bi 2001 {published data only}
    1. Bi BF, Qiu XS. The clinical observation of three drug treatments for ectopic pregnancy. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 2001;11(10):635‐6.
Bu 2004 {published data only}
    1. Bu YG, Zhu BL. Combined use of single‐dose methotrexate intramuscular injection and mifepristone in treating ectopic pregnancy. Acta University Medicinalis Anhui 2004;39(1):71‐3.
Cai 1998a {published data only}
    1. Cai CR, Pu YQ, Zheng XL. The effect comparison of methotrexate used alone or combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Current Advances in Obstetrics and Gynecology 1998;7(3):280‐1.
Cai 1998b {published data only}
    1. Cai M, Yang ZW. The clinical observation of mifepristone combined with traditional Chinese medicine in the treatment of ectopic pregnancy. Hunan Guiding Journal of TCMP 1998;4(5):20.
Cao 2003 {published data only}
    1. Cao YM, Li JX, Qin XN. Observation of curative effect of integrated Chinese traditional and Western medicine herbs in treating the ectopic pregnancy in 30 cases. Modern Medicine Health 2003;19(7):815‐6.
Chang 2009 {published data only}
    1. Chang XM. The clinical observation of traditional Chinese medicine combined with western medicine in the treatment for 40 cases ectopic pregnancy. Chinese Journal Modern Drug Apply 2009;3(7):95‐6.
Che 2007 {published data only}
    1. Che CY, Yang XF. The effect observation of combined traditional Chinese medicine with methotrexate in the treatment for 34 cases of ectopic pregnancy. Central Plains Medical Journal 2006;33(14):79.
Chen 1999 {published data only}
    1. Chen JF. The comparison of four kinds of non‐surgical conservative treatments for ectopic pregnancy. Central Plains Medical Journal 1999;26(3):7‐8.
Chen 2003a {published data only}
    1. Chen P, Xie TQ, Wu ZB, Wu J, Yan EL, Wu FQ. The report of methotrexate and mifepristone combined with tradition Chinese medicine in the treatment for 38 cases of tubal pregnancy. Medical Journal of Casc 2003;5(6):53‐4.
Chen 2003b {published data only}
    1. Chen JX. The clinical observation of mifepristone combined with traditional Chinese medicine in the treatment for tubal pregnancy. Acta Academiae Medicinae Xuzhou 2003;23(6):569‐70.
Chen 2004 {published data only}
    1. Chen H, Zhang CY. The effect observation of traditional Chinese medicine combined with Western medicine for treating ectopic pregnancy. Journal of Practical Traditional Chinese Medicine 2004;20(10):567.
Chen 2008 {published data only}
    1. Chen AZ. The application of mifepristone and Chinese herb in ectopic pregnancy. China Practical Medicine 2008;3(18):123‐4.
Cheng 2003 {published data only}
    1. Cheng L. The observation of drug conservative treatment for 38 cases of ectopic pregnancy. Journal of Practical Traditional Chinese Medicine 2003;19(9):458.
Cheng 2007a {published data only}
    1. Chen FR. Traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy in 41 cases. Modern Journal of Integ rated Traditional Chinese and Western Medicine 2007;16(35):5264‐5.
Cheng 2007b {published data only}
    1. Chen LM, Zhao L, Gu X. Traditional Chinese medicine combined with western medicine in the treatment for ectopic pregnancy. Journal of Occupational Health and Damage 2007;22(3):233‐4.
Cheng 2009 {published data only}
    1. Chen BH, Wei M, Cao LY. Evaluation on the contribution of Chinese herbs in conservative therapy of unruptured tubal pregnancy. Chinese Hospital Pharmacy Journal 2009;29(10):835‐7.
Cui 2003a {published data only}
    1. Cui TT. The clinical summarization of traditional Chinese medicine combined with Western medicine in the treatment for 20 cases of early ectopic pregnancy [Clinic summarization on combined TCM and West medicine to treating 20 cases of early ectopic pregnancy]. Hunan Guiding Journal of TCM 2003;9(5):38‐9.
Cui 2003b {published data only}
    1. Cui LN. The analysis of traditional Chinese medicine combined with Western medicine in the treatment for 230 cases of early ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2003;12(15):1604‐5.
Dai 2000 {published data only}
    1. Dai HP. The effective of methotrexate combined Chinese herb medicine in the treatment of unruptured ectopic pregnancy. Clinical Medical Journal of China 2000;7(2):172‐3.
Dai 2007 {published data only}
    1. Dai JD. The clinical analysis of traditional Chinese medicine combined with western medicine in the treatment for 35 cases ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2007;16(17):2369‐70.
Dai 2010 {published data only}
    1. Dai J, Cui JL, Chen YF. The clinical analysis about of two kinds of methods influence β ‐ hCG plateau in the treatment of ectopic pregnancy. Chinese Journal of Ethnomedicine and Ethnopharmacy 2010;19(11):188‐9.
Dan 2001 {published data only}
    1. Dan SF, Han XS, Cai ZY, San P. The comparison of three kinds of conservative treatments for ectopic pregnancy. Aerospace Medicine 2001;12(4):201‐2.
Deng 2008 {published data only}
    1. Deng HQ. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for tubal pregnancy. Maternal and Child Health Care of China 2008;23(14):1924‐5.
Ding 2005 {published data only}
    1. Ding XL. The effect observation of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(14):1847.
Fan 2001 {published data only}
    1. Fan LL. The effect observation of three drugs for ectopic pregnancy. Qinghai Medical Journal 2001;31(6):24‐5.
Fang 2001 {published data only}
    1. Fang X. Clinical observation of integration of traditional Chinese medicine and Western medicine on heterotopic pregnancy. Hebei Journal of Traditional Chinese Medicine 2001;23(8):618‐9.
Feng 2007 {published data only}
    1. Feng XY. The effect comparison of three different conservation treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2007;16(7):949‐50.
Fu 2009 {published data only}
    1. Fu Q, Li Y. The clinical observation of mifepristone combined with methotrexate and traditional Chinese medicine in the treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2009;18(6):1996‐97.
Gang 2004 {published data only}
    1. Gang XF, Zhao XH, Zhang LX. The clinical analysis of conservative drug treatment for ectopic pregnancy. Journal of Practical Medical Techniques 2004;11(5A):613‐4.
Gao 2003 {published data only}
    1. Gao JZ. The effect observation of partner treatment of traditional Chinese medicine for unruptured ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2003;23(1):71.
Gao 2004 {published data only}
    1. Gao HL, Gao F. Traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy in 85 cases. Journal of Practical Medical Techniques 2004;11(5A):613‐4.
Gao 2006 {published data only}
    1. Gao MJ, Liu QY. The observation of traditional Chinese medicine combined with Western medicine in the treatment for 100 cases of ectopic pregnancy. Journal of Practical Traditional Chinese Internal Medicine 2006;20(1):49.
Ge 2000 {published data only}
    1. Ge ZP. Methotrexate combined with traditional Chinese medicine in the treatment for 31 cases of ectopic pregnancy. Acta Academiae Medicinae Suzhou 2000;20(2):162‐3.
Gu 2008a {published data only}
    1. Gu JR. Observation of curative effects of three therapeutic schemes for unruptured ectopic pregnancy. China Modern Doctor 2008;46(32):90‐1.
Gu 2008b {published data only}
    1. Gu JR. The effect observation of different medIcine in the treatment for unruptured ectopic pregnancy. Journal of Chinese Rural Physician 2008;10(199):91.
Guo 2003 {published data only}
    1. Guo XY, Yang QS, Xia P. Methotrexate combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Journal of Information on TCM 2003;10(2):46.
Guo 2004 {published data only}
    1. Guo XJ. The clinical analysis of conservative treatment for early ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2004;13(12):1580‐1.
Guo 2005 {published data only}
    1. Guo J. Traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy in 47 cases. Traditional Chinese Medicinal Research 2005;18(8):36‐7.
Guo 2008 {published data only}
    1. Guo R. Observation of curative effect of the four methods about conservative treatment of ectopic pregnancy. Modern Hospital 2008;8(7):66‐7.
Guo 2009a {published data only}
    1. Guo HM, Tian Y, Liang CF. The clinical study of MTX combined with shaofuzhuyu decoction in the treatment of ectopic pregnancy. He Bei Medcine 2009;15(2):143‐6.
Guo 2009b {published data only}
    1. Guo XZ. The observation of methotrexate and mifepristone combined with traditional Chinese medicine treating ectopic pregnancy. China Journal of Clinical Rational Drug Use 2009;2(2):40‐1.
Han 2004 {published data only}
    1. Han Y, Wang ZH. The effective of traditional Chinese medicine combined with Western medicine for 50 cases of ectopic pregnancy. The Journal of Medical Theory and Practice 2004;17(11):1307‐8.
Hao 2007 {published data only}
    1. Hao FX, Guo YY. Traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Modern Traditional Chinese Medicine 2007;27(4):32‐3.
Hao 2009 {published data only}
    1. Hao XH, G YH, WANG XX. The analysis of mifepristone combined with traditional Chinese medicine in the conservative treatments for ectopic pregnancy. Hebei Medical Journal 2009;31(15):1943‐4.
He 2005 {published data only}
    1. He LP, Li QC. The clinical observation of methotrexate combined with traditional Chinese medicine in the treatment for 63 cases of ectopic pregnancy. Jiangxi Journal of Traditional Chinese Medicine 2005;36(267):32‐3.
He 2008 {published data only}
    1. He WM. The effect observation of methotrexate combined with traditional Chinese medicine conservative treatment for ectopic pregnancy.. Maternal and Child Health Care of China 2008;23(31):4516‐7.
He 2009 {published data only}
    1. He YL, Zhou XL. The clinical research of methotrexate and mifepristone combined with traditional Chinese medicine treating ectopic pregnancy. China Foreign Medical Treatment 2009;28(26):76‐7.
He 2010a {published data only}
    1. He HJ, Lin SM, Liang MR. The effect of traditional Chinese medicine combined with Western medicine for treating ectopic pregnancy. Medical Information 2010;5(8):2275‐6.
He 2010b {published data only}
    1. He CQ, Tian Y, Li M. Clinical research on prevention of recurrent ectopic pregnancy with comprehensive traditional medicine therapy. Heilingjiang Medical Journal 2010;34(2):126‐8.
Hong 2004 {published data only}
    1. Hong L, Liu YJ. The clinical observation of integrated traditional and Western medicine in the treatment for unruptured ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2004;24(11):1018‐9. - PubMed
Hou 2005a {published data only}
    1. Hou BP. Co‐triplex drugs used in the treatment of unruptured tubal pregnancy. Maternal and Child Health Care of China 2005;20(6):727‐8.
Hou 2008a {published data only}
    1. Hou YM. The effect observation of conservative treatment for 102 cases ectopic pregnancy. Hebei Medical Journal 2008;30(5):652‐3.
Hu 2000 {published data only}
    1. Hu XH, Li WH. The understanding of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Chinese Journal of Information on TCM 2000;7(10):56‐7.
Hu 2001 {published data only}
    1. Hu LQ, Yang JZ. The effect analysis of methotrexate combined with traditional Chinese medicine treating ectopic pregnancy. Journal of Gannan Medical College 2001;21(3):331‐2.
Hu 2008 {published data only}
    1. Hu MH. The effect observation of methotrexate combined with traditional Chinese medicine for ectopic pregnancy. Proceeding of Clinical Medicine 2008;1(6):155‐6.
Hua 2009 {published data only}
    1. Hua XY, Li YX, Hu YG, Shang JW, Zhang JF. Traditional Chinese medicine combined with western medicine in the treatment for 36 cases of ectopic pregnancy. Journal GanSu College of Traditional Medicine 2009;26(2):33‐4.
Huang 1999 {published data only}
    1. Huang AP. The effect observation of methotrexate intravenous injection combined with traditional Chinese medicine in the conservative treatment of ectopic pregnancy. Journal of Guangdong Medical College 1999;17(3):259‐60.
Huang 2000 {published data only}
    1. Huang Y, Gu CW. Single dose of methotrexate combined with traditional Chinese medicine in the treatment for unruptured ectopic pregnancy. Journal of Sichuan Continuing Education College of Medical Science 2000;19(3):175‐6.
Huang 2004 {published data only}
    1. Huang JM. The clinical observation of traditional Chinese Medicine combined with methotrexate by intramuscular injection in the treatment for ectopic pregnancy. Chinese Journal of Clinical Medical Research 2004;10(89):1079‐80.
Huang 2006 {published data only}
    1. Huang ZJ, Tan QW, Chen RQ. The study on the clinical effect of the method of partial injection of methotrexate with Chinese native medicine treatment for curing tubal pregnancy.. Journal of Clinical and Experimental Medicine 2006;5(8):1081‐2.
Huang 2008 {published data only}
    1. Huang PY. The clinical analysis of methotrexate intramuscular injection combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Community Doctor 2008;10(184):82.
Huo 2005b {published data only}
    1. Huo J. The clinical observation of traditional Chinese medicine combined with Western medicine in the treatment for 140 cases of ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(10):1266.
Huo 2008b {published data only}
    1. Huo DZ, He JM. Mifepristone combined with TCD( Traditional Chinese Drug) treat tubal pregnancy. Journal of Zhejiang University of Traditional Chinese Medicine 2008;32(2):191‐2.
Ji 2001 {published data only}
    1. Ji LP, Xi YL. The clinical analysis of methotrexate combined with traditional Chinese medicine in the treatment for 30 cases of ectopic pregnancy. Journal of Shanxi Medical University 2001;32(1):66.
Ji 2002 {published data only}
    1. Ji QX. The comparison of three kinds of drug treatments for ectopic pregnancy. Journal of Chinese Physician 2002;4(11):1274‐5.
Jiang 2003 {published data only}
    1. Jiang FL. The clinical effective of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. American Journal Chinese Medicine 2003;5(1):41‐2.
Jiang 2004 {published data only}
    1. Jiang XX, Kong XL. Traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy in 20 cases. Shandong Journal of Traditional Chinese Medicine 2004;23(5):292‐3.
Jiang 2007 {published data only}
    1. Jiang WH. The effect observation of mifepristone combined with methotrexate and traditional Chinese medicine in the conservative treatment for ectopic pregnancy. Anhui Medical and Pharmaceutical Journal 2007;10(6):509.
Jin 2007a {published data only}
    1. Jin XX. Choice of different drug treatment and operation opportunity about heterotopic pregnancy. Journal North China Coal Medical College 2007;9(6):767‐9.
Jin 2007b {published data only}
    1. Jin M. The effect observation of methotrexate combined with traditional Chinese medicine or methotrexate used alone in the treatment for ectopic pregnancy. China Healthcare Innovation 2007;1(2):83‐84.
Jin 2007c {published data only}
    1. Jin XX. Observation on the curative effect of methotrexate combined with mifepristone and Chinese crude drug in the treatment of ectopic pregnancy. China Contemporary Medcine 2007, (19):6‐7.
Kuang 2008a {published data only}
    1. Kuang FX. The effect observation of three drugs for ectopic pregnancy. Guiding Journal of Chinese Traditional Medicind 2008;14(2):39‐40,46.
Kuang 2008b {published data only}
    1. Kuang GR, Lei L, Xu Y. The clinical application of mifepristone combined with traditional Chinese medicine in the conservative treatment for ectopic pregnancy. Journal of Clinical and Experimental Medicine 2008;7(7):132.
Lei 2005 {published data only}
    1. Lei SX, Sha JF, Zhou Q. The clinical observation of traditional Chinese medicine combined with mifepristone in the treatment for ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2005;25(12):1073.
Li 2001a {published data only}
    1. Li P. The report of mifepristone combined with traditional Chinese medicine in the treatment for 40 cases of ectopic pregnancy. Guangxi Medical Journal 2001;23(5):1296‐7.
Li 2001b {published data only}
    1. Li SP. Traditional Chinese medicine combined with Western medicine in the treatment for 40 cases of ectopic pregnancy. Journal of Practical Traditional Chinese Medicine 2001;17(3):22.
Li 2003 {published data only}
    1. Li Y, Xiang XH. The clinical observation of traditional Chinese medicine combined with Western medicine in the treatment for 42 cases of ectopic pregnancy. Yunan Journal of Traditional Chinese Medicine and Materia Medica 2003;24(3):20‐1.
Li 2004a {published data only}
    1. Li SY. Mifepristone united traditional Chinese medicine treating ectopic pregnancy of clinical analysis. Chinese Journal of the Practical Chinese with Modern Medicine 2004;4(17):419‐20.
Li 2004b {published data only}
    1. Li J. The clinical research of traditional Chinese medicine combined with mifepristone in the treatment for ectopic pregnancy. Hebei Journal of Traditional Chinese Medicine 2004;26(11):857‐8.
Li 2004d {published data only}
    1. Li RH. The analysis of mifepristone combined with traditional Chinese medicine in the treatment for 30 cases of ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2004;13(17):2246.
Li 2004e {published data only}
    1. Li P. The effect comparison of three kinds of conservative treatments for ectopic pregnancy. Journal of Guangxi Medical University 2004;21(1):59‐60.
Li 2004f {published data only}
    1. Li SF. The clinical comparison of two kinds of drug treatments for ectopic pregnancy. Clinical Medicine 2004;24(12):43‐4.
Li 2004g {published data only}
    1. Li RL, Zhao J. The comparison of two kinds of treatments of traditional Chinese medicine combined with Western medicine for ectopic pregnancy. Acta Chinese Medicine and Pharmacology 2004;32(1):26‐8.
Li 2004h {published data only}
    1. Li SH, Sun TX, Wang DL. Traditional Chinese medicine combined with methotrexate in the treatment for 44 cases of ectopic pregnancy. China's Naturopathy 2004;12(10):56‐7.
Li 2005a {published data only}
    1. Li T, Shi L, Feng DL. The effect of combining traditional Chinese medicine and Western medicine to treat ectopic pregnancy. Study Journal of Traditional Chinese Medicine 2005;23(4):741‐2.
Li 2005b {published data only}
    1. Li LL. The observation of traditional Chinese medicine combined with Western medicine in the treatment for 30 cases of ectopic pregnancy. Journal of Practical Traditional Chinese Medicine 2005;21(12):737.
Li 2006 {published data only}
    1. Li XF, Wu J, Li H. The effect of traditional Chinese medicine on preserving fertility in laparoscopic surgery treated tubal pregnancy patients. Journal South Medicine University 2006;26(6):790‐1.
Li 2007 {published data only}
    1. Li QM. The effect observation of two kinds of methods in the conservation treatment of ectopic pregnancy. China Foreign Medical Treatment 2007;24(24):4‐5.
Li 2008a {published data only}
    1. Li MX. Methotrexate combined with traditional Chinese medicine in the treatment for 34 cases ectopic pregnancy. Henan Traditional Chinese Medicine 2008;28(9):70‐1.
Li 2008b {published data only}
    1. Li L, Zhou ZX, Gao X. An analysis on the effectiveness of traditional Chinese Medicine in preventing persist ectopic pregnancy after laparoscopic operation. Journal of Minmially Invasive Medcine, 2008;3(5):443‐5.
Li 2008c {published data only}
    1. Li P. The clinical observation of two kinds of methods in the conservation treatment for 102 cases of ectopic pregnancy. Guide of China Medicine 2008;6(24):88.
Li 2008d {published data only}
    1. Li MQ. The effect observation of mifepristone combined with traditional Chinese medicine or methotrexate alone used in the treatment for ectopic pregnancy. Chinese Medicine of Factory and Mine 2008;21(5):605.
Li 2009 {published data only}
    1. Li JE. The clinical observation of traditional Chinese medicine combined with Western medicine in the treatment for 50 cases of ectopic pregnancy. Chinese journal of ethnomedicine and ethnopharmacy 2009;18(24):132.
Li 2009b {published data only}
    1. Li YH, Zhou XM, Ye ZG, Peng BL, Ren DJ, Huang HY. Effect of nursing and combination therapy with methotrexate and traditional Chinese medicine on ectopic re pregnancy after tubal pregnancy. Journal of Hainan Medical College 2009;15(7):801‐3.
Li 2010 {published data only}
    1. Li XF. The analysis of mifepristone combined with traditional Chinese medicine in the treatments for 32 cases ectopic pregnancy. China Practical Medicine 2010;5(13):150‐1.
Liang 2004 {published data only}
    1. Liang SL, Luo LP, Li YJ. The clinical analysis of mifepristone combined with traditional Chinese medicine in the treatment for 23 cases of ectopic pregnancy. Journal of Chinese Clinical Medicine Research 2004;124:136‐7.
Liang 2009 {published data only}
    1. Liang XK, Zhang Y. Small dose of intramuscular methotrexate combined with traditional Chinese medicine in the course treatment for unruptured ectopic pregnancy. Journal of Liao Ning Medical 2009;23(2):102‐3.
Liao 2001 {published data only}
    1. Liao XQ. The analysis of methotrexate intramuscular injection combined with traditional Chinese medicine in the treatment for 18 cases of ectopic pregnancy. Journal of Youjiang Medical College for Nationalities 2001;23(4):590‐1.
Lin 2007 {published data only}
    1. Lin L. The effect observation of two kinds of methods in the conservation treatment of ectopic pregnancy. China Practial Medicine 2007;2(7):99‐100.
Ling 2003 {published data only}
    1. Ling CB. The effect observation of traditional Chinese medicine combined with Western medicine for treating ectopic pregnancy. Guangxi Journal of Traditional Chinese Medicine 2003;26(3):25.
Ling 2005 {published data only}
    1. Ling WL, Wu XY. Clinical study of co‐triplex drugs used in treatment of ectopic pregnancy. Maternal and Child Health Care of China 2005;20(9):1120‐2.
Liu 1999a {published data only}
    1. Liu YJ, Nong WZ. The clinical comparison of single‐dose methotrexate intramuscular injection or combined with traditional Chinese medicine. Guangxi Medical Journal 1999;21(2):344‐5.
Liu 1999b {published data only}
    1. Liu YH, Yang BL, Wang YH. Traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Chinese Journal of Critical Care Medicine 1999;7:415.
Liu 2001 {published data only}
    1. Liu ML, Xiong HJ. The effect observation of two kinds of drug conservative treatment for ectopic pregnancy. Journal of North China Coal Medical College 2001;3(1):83.
Liu 2003 {published data only}
    1. Liu YJ, Liu XH. The effect observation of methotrexate combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Medical Forum 2003;24(13):43‐4.
Liu 2004a {published data only}
    1. Liu CF, Xia FY, Xing J. Cannula injection drug by hysteroscope combined with traditional Chinese medicine treating tubal pregnancy. Journal of Sichuan of Traditonal Chinese Medicine 2004;22(11):66‐7.
Liu 2004b {published data only}
    1. Liu M, Huang XQ. The analysis of mifepristone combined with methotrexate in the treatment for 42 cases of ectopic pregnancy. Qingdao Medical Journal 2004;36(4):263‐4.
Liu 2004c {published data only}
    1. Liu XF. The effect observation of treatment based on syndrome differentiation for ectopic pregnancy. Liaoning Journal of Traditional Chinese Medicine 2004;31(10):846.
Liu 2006 {published data only}
    1. Liu XH, Xiao YL. The clinical effect observation of methotrexate combined with traditional Chinese medicine in the treatment for tubal pregnancy. Chong Qing Medicine 2006;35(21):1988‐9.
Liu 2009a {published data only}
    1. Liu YY. The clinical effect observation of mifepristone combined with traditional Chinese medicine and microwave in the treatment for 50 cases of ectopic pregnancy. Contemporary Medicine 2009;15(19):68‐9.
Liu 2009b {published data only}
    1. Liu HF. The clinical observation of methotrexate combined with traditional Chinese medicine in the treatment for ectopic pregnancy. International Medicine & Health Guidance News 2009;15(10):74‐75.
Liu 2010 {published data only}
    1. Liu FJ. The effect observation of methotrexate combined with traditional Chinese medicine for ectopic pregnancy. Journal of Practical Traditional Chinese Medicine 2010;26(4):249.
Lu 2000a {published data only}
    1. Lu SH. The analysis of therapeutic effects of MTX and Chinese medicine No. 2 for the treatment of tubal pregnancy. Medical Journal of Casc Industry 2000;2(1):28‐9.
Lu 2000b {published data only}
    1. Lu XF. The effect observation of mifepristone combined with traditional Chinese medicine treating 88 cases of ectopic pregnancy. Medical Journal of Casc industry 2000;2(4):60.
Lu 2001 {published data only}
    1. Lu GF. Protein of Trichosanthin combined with traditional Chinese medicine in the treatment for ectopic pregnancy (an analysis of 44 cases). Journal Traditional of Chinese Medicine 2001;16(92):57‐8.
Lu 2002 {published data only}
    1. Lu LJ, Jin XR. The effect observation of drug treatment for ectopic pregnancy. Zhejiang Medical Journal 2002;24(11):694‐6.
Lu 2004 {published data only}
    1. Lu JM. Traditional Chinese medicine combined with Western medicine in the treatment for 38 cases of ectopic pregnancy. Chinese Journal of Reproductive Health 2004;15(6):354‐5.
Luo 2000 {published data only}
    1. Luo L. The effect observation of traditional Chinese medicine combined with methotrexate in the treatment for ectopic pregnancy. Journal of Sichuan Continuing Education College of Medical Sciences 2000;19(4):271,273.
Luo 2003 {published data only}
    1. Luo DF, Zhang JP, Chen YG. The effect observation of traditional Chinese medicine combined with Western medicine in the treatment for 33 cases of ectopic pregnancy. New Journal of Traditional Chinese Medicine 2003;35(12):39‐40.
Luo 2005 {published data only}
    1. Luo J, Liu L. The comparison of three conservative treatments for ectopic pregnancy. Journal of Clinical Research 2005;22(3):356‐7.
Luo 2006 {published data only}
    1. Luo ZM. The effect observation of mifepristone combined with traditional Chinese medicine for ectopic pregnancy. Hainan Medical Journal 2006;17(1):93.
Ma 2003 {published data only}
    1. Ma SX. The observation and nursing of conservative treatment for ectopic pregnancy. Shandong Medical Journal 2003;43(26):64.
Ma 2008 {published data only}
    1. Ma XL. Clinical observation on mifepristone combined with Chinese herbs in treating ectopic pregnancy. Shanghai Journal Traditional Chinese Medicine 2009;43(1):52‐4.
Mao 2004 {published data only}
    1. Mao LF, Liu LB, Yang HF. The observation of the conservative treatment for 114 cases of tubal pregnancy. Medicine and Pharmacy of Yunnan 2004;25(1):50‐1.
Mei 2005 {published data only}
    1. Mei RS. The clinical analysis of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Study Journal of Traditional Chinese Medicine 2005;23(7):1345‐6.
Meng 2000 {published data only}
    1. Meng XH, Sui XJ, Zhang JM. The clinical observation of traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy. Chinese Journal of Coal Industry Medicine 2000;3(10):1071.
Meng 2005 {published data only}
    1. Meng QF, Sheng XY. Traditional Chinese medicine combined with Western medicine in the treatment for 20 cases of ectopic pregnancy. Chinese Journal of Surgery of Integrated Traditional and Western Medicine 2005;11(4):321‐2.
Mo 2007 {published data only}
    1. Mo DM, Hai HL, Zhang H. The clinical observation of traditional Chinese medicine combined with western medicine in the treatment for 32 cases ectopic pregnancy. China Medical HeraldMEDICAL HERALD 2007;4(2):72,86.
Ni 2010 {published data only}
    1. Ni XR, Chen RD. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for tubal pregnancy. China Practical Medcal 2010;5(8):132‐3.
Pan 2007 {published data only}
    1. Pan YP. The clinical analysis of conservative treatment for 60 cases of ectopic pregnancy. China Practical Medicine 2007;12(32):114‐5.
Peng 1997 {published data only}
    1. Peng LX. Three expectant treatments for ectopic pregnancy (including the analysis of 97cases). Guangxi Medical Journal 1997;19(5):752‐4.
Qi 2000 {published data only}
    1. Qi XX, Xie ZQ, Zhao L, Zhen P. The initial approach of traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Sichuan Continuing Education College of Medical Sciences 2000;19(2):110‐1.
Qian 2008 {published data only}
    1. Qian L. The effect observation of traditional Chinese medicine combined with western medicine in the conservation treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2008;17(17):2641‐2.
Qin 2001 {published data only}
    1. Qin CY, Wang Y, Ding HY. The clinical observation of methotrexate combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Journal of Birth Health & Heredity 2001;9(6):37.
Qin 2008 {published data only}
    1. Qin LH, Shang JB. The effect comparison of different conservation treatment for early tubal pregnancy. Hebei Journal Traditional Chinese Medicine 2008;30(3):253‐254.
Qiu 2006 {published data only}
    1. Qiu CH, Zhu XY. The effect of traditional Chinese medicine on MTX in the treatment for unruptured ectopic pregnancy. Clinical Journal of Traditional Chinese Medicine 2006;18(2):163‐4.
Qu 2004 {published data only}
    1. Qu LP, Guo YW. Comparison the three kinds of methods for the treatment of tubal pregnancy. Hunan Guiding Journal of TCM 2004;10(4):26‐7,45.
Ren 2009a {published data only}
    1. Ren HW, Liu CL, Sun YP. The effect observation of methotrexate combined with traditional Chinese medicine for ectopic pregnancy. Journal of China‐Japan Friendship Hospital 2009;23(4):226‐7.
Ren 2009b {published data only}
    1. Ren GX, Liu XX. The analysis of methotrexate combined with traditional Chinese medicine in the treatment for 85 cases of ectopic pregnancy. Medical Journal of Chinese People's Health 2009;21(10):1133,1153.
Shen 2008 {published data only}
    1. Shen Q. The clinical research of three drug methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Medicine of Factory and Mine 2008;21(1):43‐4.
Shi 2000 {published data only}
    1. Shi YQ. The effect observation of traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy. Chinese Journal of Integrated Tradtional and Western Medicine 2000;20(2):149‐50.
Shi 2004 {published data only}
    1. Shi LL. The clinical observation of traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy in 68 cases. Jiangsu Journal of Traditional Chinese Medicine 2004;25(11):35‐6.
Shi 2009 {published data only}
    1. Shi F, Ye XP, Guo YL. The clinical observation of different methods using drug in the conservation treatment of ectopic pregnancy. Shan Xi Medical Journal 2009;38(7):895‐6.
Shi 2010 {published data only}
    1. Shi XY. The effect observation of two methods in the conservative treatment for early ectopic pregnancy. Chinese Journal Modern Drug Apply 2010;4(11):63‐4.
Song 2000a {published data only}
    1. Song LX. The comparison of two kinds of drug treatments for ectopic pregnancy. Hebei Medical Journal 2000;22(6):439‐40.
Song 2000b {published data only}
    1. Song JR, Wang P, Tian JX. The observation of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy in 36 cases. Heilongjiang Medicine and Pharmacy 2000;23(5):83‐4.
Song 2002 {published data only}
    1. Song HJ. The analysis of fours kinds of methods in the treatment of 183 cases of ectopic pregnancy. Medicine of Factory and Mine 2002;15(3):227‐8.
Song 2003 {published data only}
    1. Song XL. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for tubal pregnancy. Modern Medicine Health 2003;19(3):310‐1.
Song 2004 {published data only}
    1. Song XM. Traditional Chinese medicine combined with Western medicine treating 30 cases of ectopic pregnancy. Journal of Sichuan of Traditional Chinese Medicine 2004;22(8):66‐7.
Su 2002 {published data only}
    1. Su Y, Sun Y, Ma L, Zhang SX. Observation on treatment of ectopic pregnancy by combination therapy of Chinese herbal medicine with mifepristone or methotrexate. Chinese Journal of Integrated Traditional and Western Medicine 2002;22(6):417‐9. - PubMed
Su 2005 {published data only}
    1. Su W. The clinical application of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Liaoning Journal of Traditional Chinese Medicine 2005;32(6):574‐5.
Su 2006 {published data only}
    1. Su LY, Si XY, Ma GL. Research of Heterotopic Pregnancy Treated By TCM. Chinese Modern Traditional Chinese Medicine 2010;8(5):23,40.
Sun 2003 {published data only}
    1. Sun HJ, Zhang XY. The effect observation of traditional Chinese medicine combined with Western medicine in the treatment for 25 cases of ectopic pregnancy. Practical Journal of Rural Doctor 2003;10(1):35‐6.
Sun 2004 {published data only}
    1. Sun JX, Wang HY, Liu JM. The clinical analysis of methotrexate combined with traditIonal Chinese medicine in the treatment for 32 cases of ectopic pregnancy. Journal of Linyi Medical College 2004;26(5):362‐3.
Sun 2007a {published data only}
    1. Sun Y, Jin F. The clinical observation of traditional Chinese medicine combined with western medicine in the treatment for 57 cases ectopic pregnancy. Zhejiang Journal of Traditional Chinese Medicine 2007;42(9):527‐8.
Sun 2007b {published data only}
    1. Sun FH. The use of mifepristone combined with traditional Chinese medicine in the conservative treatments for ectopic pregnancy. Chinese Community Doctors 2007;9(11):86.
Tang 2009 {published data only}
    1. Tang J. Traditional Chinese medicine combined with Western medicine in the conservative treatment for ectopic pregnancy. Journal of Guiyang College of Traditional Chinese Medicine 2009;31(1):45‐6.
Tian 2002a {published data only}
    1. Tian XH, Song CG. The clinical observation of mifepristone combined with composition of traditional Chinese medicine for ectopic pregnancy in 45 cases. Medical Journal of Chinese Civil Administration 2002;14(4):211‐2.
Tian 2002b {published data only}
    1. Tian JP. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Chinese Rural Physician 2002;18(19):28.
Tian 2005 {published data only}
    1. Tian XJ, Mi DH, Wang XR, Wei YH. The effective observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Academic Periodical of Changchun College of Traditional Chinese Medicine 2005;21(3):23.
Tian 2008 {published data only}
    1. Tian FY. Traditional Chinese medicine combined with methotrexate in the treatment for 33 cases of unruptured tubal pregnancy. Chinese Journal of Ethnomedicine and Ethnopharmacy 2008;17(8):68‐9.
Wang 2000a {published data only}
    1. Wang FJ, Zhong WZ, Yu XY, Chen P. The clinical analysis of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Zhejiang Practical Medicine 2000;5(2):45‐6.
Wang 2000b {published data only}
    1. Wang XM. Drug conservative treatment for ectopic pregnancy. Hebei Medicine 2000;6(7):592‐3.
Wang 2001a {published data only}
    1. Wang DX. The effective observation of mifepristone combined with traditional Chinese medicine in the treatment for 33 cases of ectopic pregnancy. Chinese Medical Therapy and Practice 2001;2001(7):854‐5.
Wang 2001b {published data only}
    1. Wang FG, Qi JP, Chen SL. The comparison of three kinds of drug treatments for ectopic pregnancy. Tianjin Journal of Traditional Chinese Medicine 2001;18(6):9.
Wang 2002 {published data only}
    1. Wang YJ. The clinical analysis of mifepristone combined with methotrexate in the treatment of 32 cases of ectopic pregnancy. Journal of Youjiang Medical College for Nationalities 2002;24(4):584‐5.
Wang 2003a {published data only}
    1. Wang YL. The effective observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Traditional Chinese Medicine and Chinese Materia Medica of Jilin 2003;23(11):27‐8.
Wang 2003b {published data only}
    1. Wang ZY, Ni W. The clinical effective of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Chinese Medicine Research 2003;3(5):432‐3.
Wang 2004a {published data only}
    1. Wang AL, Song RL. Combination of traditional Chinese medicine with Western medicine in the treatment for ectopic pregnancy. Chinese Journal of Birth Health & Heredity 2004;12(3):91.
Wang 2004b {published data only}
    1. Wang YF, Li MX, Gong Y. The analysis of methotrexate combined with tradItional Chinese medicine in the conservative treatment for 50 cases of ectopic pregnancy. Chinese General Practice 2004;7(4):269.
Wang 2004c {published data only}
    1. Wang SP, Wang JY, Sun Q, Xia CL. Methotrexate combined with traditional Chinese medicine for ectopic pregnancy. Chinese Practice Journal of Rural Doctor 2004;11(7):28.
Wang 2005a {published data only}
    1. Wang XG, Tao Y. Conservative treatment on stable tubal pregnancy by combining with traditional Chinese and Western medicine: an observation of 36 cases. Journal Gansu College of Traditional Chinese Medicine 2005;22(3):42‐3.
Wang 2005b {published data only}
    1. Wang XY. Mifepristone combined with methotrexate and traditional Chinese medicine treating ectopic pregnancy. Jiangsu Medical Journal 2005;31(12):951.
Wang 2005c {published data only}
    1. Wang SX, Sun SY. The effect observation of traditional Chinese medicine combined with Western medicine in the treatment for 100 cases of ectopic pregnancy. Chinese Archives of Traditional Chinese Medicine 2005;23(1):174.
Wang 2006a {published data only}
    1. Wang LG. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Modern Traditional Chinese Medicine 2006;26(3):27‐8.
Wang 2006b {published data only}
    1. Wang SM. The effective observation of conservation treatment 100 cases of ectopic pregnancy. China Practical Medcial 2006;1(4):101,08.
Wang 2006c {published data only}
    1. Wang SM, Yang HM. The methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy.. Medical Information 2006;19(9):1647‐8.
Wang 2007a {published data only}
    1. Wang JC. The clinical observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2007;16(2):148‐9.
Wang 2007b {published data only}
    1. Wang LH. 120 examples clinical analysis of two different medicine methods to treat tubal pregnancy. Contemporary Medicine 2007;16(15):17‐9.
Wang 2007c {published data only}
    1. Wang RL. The clinical observation in treating ectopic pregnancy. Journal of Medical Forum 2007;28(9):48‐9.
Wang 2007d {published data only}
    1. Wang PP. The effect observation of Chinese medicine No.2 combined with methotrexate and mifepristone for the treatment of tubal pregnancy. Lishizhen Medicine and Materia Medica Research 2007;18(9):2260.
Wang 2007e {published data only}
    1. Wang LH. The clinical effect observation of methotrexate combined with traditional Chinese medicine for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2007;16(15):2068.
Wang 2008 {published data only}
    1. Wang QY, Dong SJ. The clinical observation of destroying embryo and resolving lump combined with methotrexate and mifepristone in treating ectopic pregnancy. Journal of Emergency in Traditional Chinese Medicine 2008;17(5):618‐9.
Wang 2009 {published data only}
    1. Wang YF. The Clinical observation of methotrexate combined with medicinal herbs in the treatment of ectopic pregnancy. China Modern Doctor 2009;47(3):21‐2,24.
Wang 2010a {published data only}
    1. Wang Q. Traditional Chinese medicine combined with western medicine in the treatment for 34 cases of ectopic pregnancy. Chinese Medicine Modern Distance Education of China 2010;8(11):55‐6.
Wang 2010b {published data only}
    1. Wang CX, Wang XM, Jia GL. The clinical observation of methotrexate combined with traditional Chinese medicine in the treatment for tubal pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2010;19(8):942‐3.
Wei 1999 {published data only}
    1. Wei X, Lin RF, Song M. Clinical study of Sanjie Shapei Heji applied in the treatment of early ectopic pregnancy. Henan Traditional Chinese Medicine 1999;19(2):21‐3,72.
Wei 2002 {published data only}
    1. Wei LQ, Tang XH. Traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy in 53 cases. Shanxi Journal of Traditonal Chinese Medicine 2002;23(11):965‐6.
Wei 2003 {published data only}
    1. Wei FY, Chen HF. Clinical analysis of 82 cases of ectopic pregnancy treated by methotrexate combined with traditional Chinese recipe. Journal of Chinese Integrative Medicine 2003;1(4):267, 292. - PubMed
Wen 2005 {published data only}
    1. Wen WL, Wang H, Sun F. A gestation medicine cures three kinds of methods curative effect observation. International Medicine & Health Guidance News 2005;11(14):87‐8.
Wu 2001 {published data only}
    1. Wu YD, Liu B, Tang XX. The comparison of three kinds of drug treatments for ectopic pregnancy. Heilongjiang Medicine and Pharmacy 2001;24(4):82‐3.
Wu 2002 {published data only}
    1. Wu XF. Traditional Chinese medicine combined with methotrexate in the treatment for ectopic pregnancy. Primary Journal of Chinese Materia Medica 2002;16(5):60‐1.
Wu 2004a {published data only}
    1. Wu J, Song YM. Combination of MTX and traditional Chinese medicine treating ectopic pregnancy [Combination of MAX and traditional Chinese medicine treating ectopic pregnancy]. Chinese Journal of Family Planning 2004;104(6):361‐3.
Wu 2004b {published data only}
    1. Wu JX, Teng W, Zhao CL. Methotrexate combined with traditional Chinese medicine in the treatment for 18 cases of unruptured tubal pregnancy. Shanxi Journal of Traditional Chinese Medicine 2004;25(11):991‐2.
Wu 2004c {published data only}
    1. Wu YZ, Ye XC, Lin XE. The effect observation of conservative treatment for ectopic pregnancy. Strait Pharmaceutical Journal 2004;16(5):121‐3.
Wu 2009 {published data only}
    1. Wu FY. Comparative studies on ectopic pregnancy by mifepristone combined with herbal ectopic pregnancy II or MTX. Journal of Heze Medical College 2009;21(1):20‐2.
Xiong 2001 {published data only}
    1. Xiong DM, Li H. The clinical analysis of conservative treatment for 120 cases of ectopic pregnancy. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine 2001;11(1):41‐3.
Xiong 2005 {published data only}
    1. Xiong JM, He M. Clinical analysis of traditional Chinese medicine combined with methotrexate in the treatment for 80 cases of ectopic pregnancy. Modern Medicine Health 2005;21(17):2284.
Xu 2001 {published data only}
    1. Xu CH, Lin JP, He DQ. The clinical observation of compound recipe for 40 cases of ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2001;10(17):1641‐2.
Xu 2005 {published data only}
    1. Xu ZF, Liu XT. Traditional Chinese medicine in the treatment for 60 cases of ectopic pregnancy. Chinese Journal of Clinical Medicine Research 2005;11(15):2171‐2.
Xu 2008 {published data only}
    1. Xu TH. The clinical observation of mifepristone combined with traditional Chinese medicine in the treatment for 40 cases ectopic pregnancy. Contemporary Medicine 2008;2(3):173‐4.
Xue 2000 {published data only}
    1. Xue P, Zhao SX. Clinical analysis of integration of TCM and Western Medicine on heteroptics pregnancy. Hebei Journal of Traditional Chinese Medicine 2000;22(12):934‐5.
Xun 1994 {published data only}
    1. Xun AX, Liu SY, Ma HL, Zeng QL. The effective of 5‐FU combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Jinning Medical College 1994;17(2):29‐30.
Yan 2007 {published data only}
    1. Yan Y, Chai HJ. The research of traditional Chinese medicine combine with laparoscopic conservative surgery for smooth tubal in treating tubal pregnancy. Liaoning Journal of Traditional Chinese Medicine 2007;34(11):1609‐10.
Yang 1999 {published data only}
    1. Yang GP, Liu YF, Wang FY. Combination of methotrexate and traditional Chinese medicine in the treatment for unruptured ectopic pregnancy. Journal of Huaifang Medical College 1999;21(3):220.
Yang 2001 {published data only}
    1. Yang L, Yu GZ, Chen CY, Li M, He Y, Gong Y. Single‐dose methotrexate intramuscular injection combined with tradItional Chinese medicine in the treatment for 22 cases of ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2001;21(9):666.
Yang 2002 {published data only}
    1. Yang QJ, Li MW. The clinical observation of drug treatment for ectopic pregnancy. Shandong Medical Journal 2002;42(30):76.
Yang 2003 {published data only}
    1. Yang XL. Treatment of ectopic pregnancy with methotrexate combined with Chinese herbs, a report of 70 cases. Shanxi Journal of Traditional Chinese Medicine 2003;19(5):31‐2.
Yang 2005 {published data only}
    1. Yang AL, Zhou H. Experience in nursing care of pregnancy woman suffering ectopic pregnancy treated with traditional Chinese medicine combined with MTX. Journal of Qilu Nursing 2005;11(12B):1843‐4.
Yang 2008a {published data only}
    1. Yang YJ. Observations Conservative therapeutic of in ectopic pregnant case with MTX combined with RU486 and Chinese medicine. China Journal of Modern Medicine 2008;18(19):2880‐2.
Yang 2008b {published data only}
    1. Yang PZ. The clinical observation of methotrexate combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Journal of Practical Medical Techniques 2008;15(27):3703‐4.
Yang 2008c {published data only}
    1. Yang WJ, Xu ZF, Peng XP. Preventing and treating the persistent ectopic pregnancy by the decoction of ectopic pregnancy. Anhui Medical and Pharmaceutical Journal 2008;12(3):243‐4.
Ye 1999 {published data only}
    1. Ye R. The clinical analysis of drug treatments for 70 cases of early ectopic pregnancy. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 1999;9(3):206‐7.
Ye 2004 {published data only}
    1. Ye CF, Chen XL, Deng WH. The clinical observation of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. The Journal of Practical Medicine 2004;20(12):1434‐5.
Yi 1999 {published data only}
    1. Yi NY, Deng W, Zhang SY. The analysis of Yi Wei Ting capsule treating 30 cases of stable ectopic pregnancy. Chinese Journal of Critical Care Medicine 1999;19(7):426.
Yu 2005a {published data only}
    1. Yu XL. Mifepristone combined with methotrexate and traditional Chinese medicine treating 26 cases of ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(22):2958‐9.
Yu 2005b {published data only}
    1. Yu ZF. The effect comparison of four kinds of conservative treatments for ectopic pregnancy. Shanxi Medical Journal 2005;34(12):1053‐4.
Yu 2009 {published data only}
    1. Yu XF, Wang SY, Yan L. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Medical Journal West China 2009;21(9):1507‐8.
Yu 2010a {published data only}
    1. Yu DS. The clinical observation of mifepristone combined with traditional Chinese medicine in the conservation treatment for ectopic pregnancy. Hubei Journal of Traditional Chinese Medicine 2010;32(6):34‐5.
Yu 2010b {published data only}
    1. Yu T, Yang Y. The clinical observation of methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Journal of Ethnomedicine and Ethnopharmacy 2010;19(1):81‐2.
Yuan 2003 {published data only}
    1. Yuan AY. Traditional Chinese medicine combined with Western medicine in the treatment for 46 cases of ectopic pregnancy. Applied Journal of General Practice 2003;1(4):278,280.
Yuan 2005 {published data only}
    1. Yun SH. The clinical effectiveness of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Modern Medical Health 2005;21(14):1822.
Yuan 2008 {published data only}
    1. Yuan SY, Wang L, Lin YZ, Wang L. Clinical effect and influence on cell factor of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Shandong Medical Journal 2008;48(27):96‐7.
Yuan 2009 {published data only}
    1. Yuan LJ. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for 88 cases ectopic pregnancy. Aerospace Medicine 2009;20(1):39.
Zeng 2003 {published data only}
    1. Zeng GX. The effect observation of traditional Chinese medicine for ectopic pregnancy. Journal of Chenzhou Medical College 2003;5(2):26‐7.
Zeng 2004a {published data only}
    1. Zeng L, Huang GZ, Bao XW. The effective observation of different conservative treatments for ectopic pregnancy [Explore the curative effect and side effect on the different conservative treatments of ectopic pregnancy]. Liaoning Journal of Traditional Chinese Medicine 2004;31(10):843‐4.
Zeng 2004b {published data only}
    1. Zeng GH, Ou XF, Bai XH, Yu ZH, Wen YF, Wen GJ. The effect observation of methotrexate combined with traditional Chinese medicine in the treatment for tubal pregnancy. New Chinese Medical of Journal 2004;5(5):426‐7.
Zhai 2005 {published data only}
    1. Zhai QZ, Jiang T, Sun HZ. The analysis of methotrexate combined with traditional Chinese medicine in the treatment for 100 cases of ectopic pregnancy. Journal of Jiangsu Clinical Medicine 2005;9(1):81, 83.
Zhang 2000a {published data only}
    1. Zhang Y, Shen W. The primary approach of the condition of conservative treatment for ectopic pregnancy, an analysis of 76 cases. Chinese Journal of Information on TCM 2003;10(2):46.
Zhang 2000b {published data only}
    1. Zhang XJ. The effect observation of drug treatment for ectopic pregnancy. Chinese Journal of Birth Health & Heredity 2000;8(6):52,51.
Zhang 2001 {published data only}
    1. Zhang QX. The comparison of two kinds of drug treatments for ectopic pregnancy. Shanxi Clinical Medicine Journal 2001;10(10):740‐1.
Zhang 2003a {published data only}
    1. Zhang L. The clinical observation of three drug treatments for ectopic pregnancy. Hainan Medical Journal 2003;14(12):68‐9.
Zhang 2003b {published data only}
    1. Zhang H, Li SH, Wang HQ, Shen LF, Ge HX. Traditional Chinese medicine combined with Western medicine in the treatment for 162 cases of ectopic pregnancy. China's Naturopathy 2003;11(6):7‐8.
Zhang 2004a {published data only}
    1. Zhang B. The analysis of 31 cases of ectopic pregnancy treated by methotrexate combination with traditional Chinese medicine. Journal of Shanxi Medical College for Continuing Education 2004;14(4):47‐8.
Zhang 2004b {published data only}
    1. Zhang XM. The effective observation of integrated traditional and Western medicine treating 72 cases of ectopic pregnancy. Lishizhen Medicine and Materia Medica Research 2004;15(6):330.
Zhang 2004c {published data only}
    1. Zhang JH. The analysis of methotrexate combined with traditional Chinese medicine in the treatment for 108 cases of ectopic pregnancy. Shandong Medical Journal 2004;44(6):33.
Zhang 2005 {published data only}
    1. Zhang Y, He JQ. Traditional Chinese medicine combined with Western medicine in the treatment for 32 cases of ectopic pregnancy. Chinese Journal of Information on TCM 2005;12(2):74‐5.
Zhang 2006 {published data only}
    1. Zhang QZ. The clinical analysis of methotrexate combined with traditional Chinese medicine in the treatment for 30 cases of ectopic pregnancy. Maternal and Child Health Care of China 2006;21(19):2751‐2.
Zhang 2007a {published data only}
    1. Zhang QH. The clinical observation of tradItional Chinese medicine combined with Western medicine in the treatment for 47 cases ectopic pregnancy. JOURNAL OF LIAONING UNIVERSITY OF TCM 2007;9(2):113.
Zhang 2007b {published data only}
    1. Zhang JN, Ke XH, Cheng QN, Yang JQ. Chinese medicine of activating blood and removing stasis, destroying embryo and resolving lump combined with mifepristone in treating 36 cases of ectopic pregnancy. Journal of Fujian College of Traditional Chinese Medcine 2007;17(4):5‐7.
Zhang 2008a {published data only}
    1. Zhang XH, E ZM, Guo LJ. The observation and analysis of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Chinese Journal Modern Drug Apply 2008;2(6):68‐9.
Zhang 2008b {published data only}
    1. Zhang H. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. China Practical Medicine 2008;3(22):119‐20.
Zhang 2008c {published data only}
    1. Zhang YL. The effect observation of methotrexate combined with traditional Chinese medicine for tubal pregnancy. GanSu Medical Journal 2008;27(3):55‐6.
Zhang 2009 {published data only}
    1. Zhang PQ. The clinical analysis of mifepristone and methotrexate combined with traditional Chinese medicine independently in the treatment for 50 cases of ectopic pregnancy. Medical Journal of Chinese People'health 2009;21(19):2430‐1.
Zhao 2001 {published data only}
    1. Zhao YH. The adjunctive therapy of traditional Chinese medicine for 24 cases of ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2001;21(6):466‐7.
Zhao 2002 {published data only}
    1. Zhao FQ, Ma J. Traditional Chinese medicine combined with Western medicine in the treatment for 30 cases of ectopic pregnancy. Journal of Henan College of Traditional Chinese Medicine 2002;17(5):56‐7.
Zhao 2003a {published data only}
    1. Zhao XY, Zhu YP, Xie SR. Comparison of mifepristone combined Chinese herbs and a methopterin in the treatment of ectopic pregnancy. Journal of Xinxiang Medical College 2003;20(5):342‐3.
Zhao 2003b {published data only}
    1. Zhao W, Li M. The clinical observation of three drug treatments for ectopic pregnancy. Journal of Practical Countryside Doctor 2003;10(2):35.
Zhao 2003c {published data only}
    1. Zhao X. The effect observation of mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. New Chinese Medical Journal 2003;4(22):2058‐9.
Zhao 2006a {published data only}
    1. Zhao LH. The effect observation of methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for ectopic pregnancy. Chinese Journal of Misdiagnostics 2006;6(18):3509‐10.
Zhao 2006b {published data only}
    1. Zhao CF. Analysis on 40 examples patients of Etopic gestation treated by Mifepristone Tablets with Chinese traditional medicine. Guangming Journal of Chinese Medicine 2006;21(8):18‐9.
Zhao 2009 {published data only}
    1. Zhao L, Zhang J, Fu WL, Liu YG. Comparative observation of Chinese Medicine and western medicine treatment for unruptured tubal pregnancy. Liaoning Journal of Traditional Chinese Medicine 2009;36(4):566‐7.
Zheng 2002 {published data only}
    1. Zheng WL, Lin J, He H. Methotrexate and mifepristone combined with traditional Chinese medicine in the treatment for unruptured tubal pregnancy. Guangdong Medical Journal 2002;23(Suppl.):183‐4.
Zheng 2010 {published data only}
    1. Zheng XH. The clinical experience of conservative drug treatment for ectopic pregnancy. Journal of medical forum 2010;31(2):76‐7.
Zhou 1999 {published data only}
    1. Zhou YH. The clinical analysis of traditional Chinese medicine combined with Western medicine in the treatment for 34 cases of ectopic pregnancy. Shanxi Journal of Traditional Chinese Medicine 1999;15(5):28‐9.
Zhou 2001 {published data only}
    1. Zhou ZH, Wang J. The comparison of different therapeutic regimens of methotrexate in the conservative treatment for ectopic pregnancy. Chinese Journal of Primary Medicine and Pharmacy 2001;8(3):266‐7.
Zhou 2006 {published data only}
    1. Zhou M, Luo Y. The therapeutic effects of methotrexate and mifepristone combined with the traditional Chinese drug on ectopic pregnancy. West China Medical Journal 2006;21(1):133.
Zhou 2010a {published data only}
    1. Zhou GZ, Gao YX, Zhou LW. The treatment of guizhifulintang for 60 cases of ectopic pregnancy. Chinese Medcine Modern Distance Education of China 2010;8(85):32.
Zhou 2010b {published data only}
    1. Zhou DX, Wang XM. Observation on the curative effect of MTX combined Chinese medicine in the treatment of ectopic pregnancy. National Medical Frontiers of China 2010;5(5):24,53.
Zhu 2002 {published data only}
    1. Zhu YL, Tian DL. The primary approach of conservative treatment for ectopic pregnancy. Acta Academiae Medicine Suzhou 2002;22(4):497,499.
Zhu 2003 {published data only}
    1. Zhu XM. The effect analysis of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Hebei Medical Journal 2003;25(8):610.
Zhu 2005 {published data only}
    1. Zhu XB. The clinical analysis of traditional Chinese medicine combined with Western medicine in the treatment for ectopic pregnancy. Modern Journal of Integrated Traditional Chinese and Western Medicine 2005;14(10):1264‐5.
Zhu 2007a {published data only}
    1. Zhu SQ. The clinical observation of different dose mifepristone combined with tradItional Chinese medicine in the treatment for ectopic pregnancy. Journal North China Coal Medical College 2007;9(5):681‐2.
Zhu 2007b {published data only}
    1. Zhu JW, Song JM, Wu XH. The clinical observation of single‐dose methotrexate combined with tradItional Chinese medicine in the treatment for ectopic pregnancy. Chinese Journal of Integrated Traditional and Western Medicine 2007;27(8):761‐2.
Zhu 2008 {published data only}
    1. Zhu WZ. The effect observation of methotrexate combined with mifepristone for ectopic pregnancy. Public Medical Forum Magazine 2008;12(25):814‐5.
Zhu 2009 {published data only}
    1. Zhu FF, Peng ML. The clinical observation of mifepristone combined with traditional Chinese medicine in the conservative treatment for 51cases of ectopic pregnancy. Clinical Education of General Practice 2009;7(3):308‐9.
Zhu 2010 {published data only}
    1. Zhu JF, Li SH. The most favourable plan of methotrexate combined with traditional Chinese medicine conservative treatment for ectopic pregnancy. Sichuan Medical Journal 2010;31(6):828‐9.
Zhuang 2006 {published data only}
    1. Zhuang FN, Li YH. The analysis of Chinese medicine Shenghongqi capsule in the treatment of 30 cases ectopic pregnancy. Strait Pharmaceutical Journal 2006;18(2):113‐4.

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