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Review
. 2011 May-Jun;108(3):187-94.

Glioblastoma: Part I. Current state of affairs

Michael E Salacz  1 , Kenneth R Watson, David A Schomas
Affiliations
Review

Glioblastoma: Part I. Current state of affairs

Michael E Salacz et al. Mo Med. 2011 May-Jun.

Abstract

Although uncommon, "brain cancer" is one of the most feared diseases that afflict human beings. While still regarded as one of the most deadly forms of primary brain neoplasm, recent advances in the treatment of glioblastoma (GBM) have offered new hope for patients, families, and clinicians. In the first part of this two-part review, we will focus on the multidisciplinary advances that have established the current treatment approach in the management of GBM. In the second part of this review, ongoing research will be presented including current clinical trials as well as some of the newer technologies that are forming the promise of the future.

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Figures

Image 1
Image 1
Axial MRI Image of GBM with Contrast.
Image 2
Image 2
Axial MRI, FLAIR Sequence.
Image 3
Image 3
Coronal section of frontal lobe – Glioblastoma with variable appearance of tumor leading to use of term “multiforme.”
Images 4 and 5.
Images 4 and 5.
Top: 400x photomicrograph – Glioblastoma with marked cellularity, nuclear atypia, mitotic figures (arrows), and vascular/endothelial proliferation (arrowheads). Bottom: 200x photomicrograph – Glioblastoma with pseudo-palisading of tumor cells around area of necrosis (arrows).
None
None
See this image and copyright information in PMC

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