Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 May-Jun;108(3):187-94.

Glioblastoma: Part I. Current state of affairs

Michael E Salacz  1 , Kenneth R Watson, David A Schomas
Affiliations
Review

Glioblastoma: Part I. Current state of affairs

Michael E Salacz et al. Mo Med. 2011 May-Jun.

Abstract

Although uncommon, "brain cancer" is one of the most feared diseases that afflict human beings. While still regarded as one of the most deadly forms of primary brain neoplasm, recent advances in the treatment of glioblastoma (GBM) have offered new hope for patients, families, and clinicians. In the first part of this two-part review, we will focus on the multidisciplinary advances that have established the current treatment approach in the management of GBM. In the second part of this review, ongoing research will be presented including current clinical trials as well as some of the newer technologies that are forming the promise of the future.

PubMed Disclaimer

Figures

Image 1
Image 1
Axial MRI Image of GBM with Contrast.
Image 2
Image 2
Axial MRI, FLAIR Sequence.
Image 3
Image 3
Coronal section of frontal lobe – Glioblastoma with variable appearance of tumor leading to use of term “multiforme.”
Images 4 and 5.
Images 4 and 5.
Top: 400x photomicrograph – Glioblastoma with marked cellularity, nuclear atypia, mitotic figures (arrows), and vascular/endothelial proliferation (arrowheads). Bottom: 200x photomicrograph – Glioblastoma with pseudo-palisading of tumor cells around area of necrosis (arrows).
None
None
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. CBTRUS. CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004–2006. Source Central Brain Tumor Registry of the United States; Hinsdale, IL: 2010. website: www.cbtrus.org.
    1. Porter KR, McCarthy BJ, Freels S, Kim Y, Davis FG. Prevalence estimates for primary brain tumors in the US by age, gender, behavior, and histology. Neuro–Oncology. In Press. - PMC - PubMed
    1. American Cancer Society. Cancer Facts & Figures 2009. Atlanta: American Cancer Society; 2009.
    1. Bondy ML, Scheurer ME, et al. Brain Tumor Epidemiology: Consensus from the Brain Tumor Epidemiology Consortium. Cancer Supplement. 2008 Oct 1;113(7):1953–68. - PMC - PubMed
    1. Myung SK, Ju W, McDonnell DD, et al. Mobile Phone Use and the Risk of Tumors: A Meta-Analysis. Journal Clinical Oncology. 2009 Nov 20;27(33):5565–72. - PubMed

LinkOut - more resources