Hepatocellular carcinoma: a review of the surgical approaches to management
- PMID: 21736080
- PMCID: PMC6188298
Hepatocellular carcinoma: a review of the surgical approaches to management
Abstract
Hepatocellular carcinoma (HCC) is increasing in incidence in the United States and is strongly associated with chronic liver disease and cirrhosis. Surgical therapy with liver transplantation or resection remains the mainstay of curative therapy for patients with HCC. Therapeutic decisions in patients with HCC are complex and are best approached via a multidisciplinary group of liver transplant and hepatobiliary surgeons, oncologists, and hepatologists. In this manuscript, we review the current surgical management of HCC.
Figures
Similar articles
-
From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world.World J Gastroenterol. 2017 Aug 7;23(29):5282-5294. doi: 10.3748/wjg.v23.i29.5282. World J Gastroenterol. 2017. PMID: 28839428 Free PMC article. Review.
-
Current concepts in hepatic resection for hepatocellular carcinoma in cirrhotic patients.World J Gastroenterol. 2012 Nov 28;18(44):6398-408. doi: 10.3748/wjg.v18.i44.6398. World J Gastroenterol. 2012. PMID: 23197885 Free PMC article. Review.
-
Surgical resection and liver transplantation for hepatocellular carcinoma.Clin Liver Dis. 2015 May;19(2):381-99. doi: 10.1016/j.cld.2015.01.007. Epub 2015 Mar 2. Clin Liver Dis. 2015. PMID: 25921669 Review.
-
TACE Combined with HIFU Versus Surgical Resection for Single Hepatocellular Carcinoma with Child-Pugh B Cirrhosis in Overall Survival and Progression-Free Survival: A Retrospective Study.Technol Cancer Res Treat. 2021 Jan-Dec;20:15330338211060180. doi: 10.1177/15330338211060180. Technol Cancer Res Treat. 2021. PMID: 34855560 Free PMC article.
-
Hepatocellular carcinoma in children.Clin Liver Dis. 2015 May;19(2):433-47. doi: 10.1016/j.cld.2015.01.010. Epub 2015 Feb 28. Clin Liver Dis. 2015. PMID: 25921672 Review.
Cited by
-
Effects of intratumoral injection of immunoactivator after microwave ablation on antitumor immunity in a mouse model of hepatocellular carcinoma.Exp Ther Med. 2018 Feb;15(2):1914-1917. doi: 10.3892/etm.2017.5633. Epub 2017 Dec 14. Exp Ther Med. 2018. PMID: 29434784 Free PMC article.
-
Targeted glypican-3 gene transcription inhibited the proliferation of human hepatoma cells by specific short hairpin RNA.Tumour Biol. 2013 Apr;34(2):661-8. doi: 10.1007/s13277-012-0593-y. Epub 2012 Nov 29. Tumour Biol. 2013. PMID: 23192642 Free PMC article.
-
A precise surgical planning system for hepatectomy coupled with liver tissue in the hepato-portal vein territories.Quant Imaging Med Surg. 2025 May 1;15(5):3839-3848. doi: 10.21037/qims-24-2349. Epub 2025 Apr 28. Quant Imaging Med Surg. 2025. PMID: 40384718 Free PMC article.
-
Annexin A2 silencing inhibits invasion, migration, and tumorigenic potential of hepatoma cells.World J Gastroenterol. 2013 Jun 28;19(24):3792-801. doi: 10.3748/wjg.v19.i24.3792. World J Gastroenterol. 2013. PMID: 23840117 Free PMC article.
-
Radiofrequency ablation compared to resection in early-stage hepatocellular carcinoma.HPB (Oxford). 2013 Mar;15(3):210-7. doi: 10.1111/j.1477-2574.2012.00541.x. Epub 2012 Aug 12. HPB (Oxford). 2013. PMID: 23374361 Free PMC article.
References
-
- Trevisani F, et al. Hepatocellular carcinoma in non-cirrhotic liver: a reappraisal. Dig Liver Dis. 2010;42(5):341–7. - PubMed
-
- Bharat A, et al. Pre-liver transplantation locoregional adjuvant therapy for hepatocellular carcinoma as a strategy to improve longterm survival. J Am Coll Surg. 2006;203(4):411–20. - PubMed
-
- Burrel M, et al. MRI angiography is superior to helical CT for detection of HCC prior to liver transplantation: an explant correlation. Hepatology. 2003;38(4):1034–42. - PubMed
-
- Edge SB, Byrd DR, Compton CC, et al. AJCC (American Joint Committee on Cancer) Cancer Staging Manual. New York: Springer; 2010. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical