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. 2011 Aug;21(8):608-14.
doi: 10.1016/j.annepidem.2011.04.004.

Spectrum of cardiovascular diseases inAsian-American racial/ethnic subgroups

Ariel T Holland  1 , Eric C Wong, Diane S Lauderdale, Latha P Palaniappan
Affiliations

Spectrum of cardiovascular diseases inAsian-American racial/ethnic subgroups

Ariel T Holland et al. Ann Epidemiol. 2011 Aug.

Abstract

Purpose: To compare the prevalence of coronary heart disease (CHD), stroke, and peripheral vascular disease (PVD) across Asian-American subgroups (Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese) and non-Hispanic white (NHW) subjects in a mixed-payer, outpatient health care organization in California.

Methods: Electronic health records from 2007 to 2010 were examined for 94,423 Asian and NHW patients. Age-adjusted prevalence rates of CHD, stroke, and PVD, defined by physician International Classification of Diseases, Version 9, codes, were directly standardized to the NHW population. Age-adjusted odds ratios were calculated by the use of logistic regression for each Asian subgroup, by sex, compared with NHWs.

Results: The range of age-adjusted prevalence rates were: CHD (1.7%-5.2%), stroke (0.3%-1.8%), and PVD (0.9%-3.4%). The adjusted odds ratios of CHD were significantly higher for Filipino women (1.66; 95% confidence interval; 1.13-2.43) and men (1.47, 1.05-2.06) and Asian Indian men (1.77, 1.43-2.21), and significantly lower for Chinese women (0.72, 0.55-0.94) and men (0.78, 0.65-0.93), compared with NHWs. The odds of stroke were significantly greater for Filipino women (2.02, 1.22-3.34). The odds of PVD were generally lower for all Asian subgroups.

Conclusion: There is considerable heterogeneity across Asian subgroups for prevalent CHD, stroke, and PVD. Future research should disaggregate Asian subgroups and cardiovascular outcomes to inform targeted prevention and treatment efforts.

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Figures

Figure 1
Figure 1
Age-adjusted OR of CHD, stroke, and PVD by gender and Asian subgroup compared with NHWs. The diamond indicates the point estimate and the bar represents the 95% CI. Filled diamonds indicate statistical significance compared with NHWs at p < 0.05.
See this image and copyright information in PMC

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