A case of reactive eccrine syringofibroadenoma

Abstract

Eccrine syringofibroadenoma is a rare adnexal tumor of eccrine ductal differentiation with variable clinical features. It manifests as either a solitary or multiple papules and nodules arranged in a symmetrical or linear pattern. The anatomical distribution is wide and includes the face, trunk, extremities, and rarely the nails. Histopathological findings show anastomosing cords and strands of uniform cuboidal cells surrounded by fibrovascular stroma. Herein, we report a case of reactive eccrine syringofibroadenoma which developed on the foot of a 37-year-old woman, after self-paring of tissue and subsequent infection and ulceration.

Keywords: Reactive eccrine syringofibroadenoma; Ulcer.

Fig. 1

Multiple, coalescing, firm, flesh-colored nodules associated with areas of crusting on the left foot. The nodules show a 'streusel bread'-like surface.

Fig. 2

(A) On histopathological examination, thin anastomosing strands of uniform, small epithelial cells arising from the epidermis to the dermis were observed (H&E, ×40). (B) The cells were embedded in a cellular fibrous stroma and exhibited a latticed pattern characteristic of eccrine syringofibroadenoma (H&E, ×100).