Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jun;60(6):416-21.
doi: 10.4097/kjae.2011.60.6.416. Epub 2011 Jun 17.

Postoperative nausea and vomiting after endoscopic thyroidectomy: total intravenous vs. balanced anesthesia

Gunn Hee Kim  1 , Hyun Joo Ahn, Hyun-Soo Kim, Si Ra Bang, Hyun-Sung Cho, Mikyung Yang, Jie Ae Kim
Affiliations

Postoperative nausea and vomiting after endoscopic thyroidectomy: total intravenous vs. balanced anesthesia

Gunn Hee Kim et al. Korean J Anesthesiol. 2011 Jun.

Abstract

Background: Endoscopic thyroidectomy was recently introduced and has been rapidly accepted by surgeons and patients. The present study was conducted to estimate and compare the incidences of postoperative nausea and vomiting (PONV) after endoscopic thyroidectomy using two different anesthetic methods: sevoflurane based balanced anesthesia; total intravenous anesthesia (TIVA).

Methods: Ninety nine female patients that were scheduled to undergo elective endoscopic thyroidectomy under general anesthesia were enrolled. These patients were randomly allocated to receive sevoflurane based balanced anesthesia (BA group) or propofol-remifentanil anesthesia (TIVA group). PONV was evaluated using a 4-point Likert scale, and pain using a visual analogue scale (VAS; range 0 to 100) for 0-2, 2-6, and 6-24 hours postoperatively. At 24 hours postoperatively, overall patient satisfaction regarding PONV and pain were recorded.

Results: The incidence of PONV was 14.6% in the TIVA group and 51.3% in the BA group. The incidence of nausea at 0-2 and 2-6 hours postoperatively was lower in the TIVA group than in the BA group (4.2% vs. 35.9%, 6.3% vs. 23.1%, respectively), but no between-group difference was observed at 6-24 hours postoperatively (8.3% vs. 5.1%). Antiemetic usage at 0-2 and 2-6 hours was lower in the TIVA than the BA group (4.2% vs. 38.5%, 6.3% vs. 23.1%), but no between-group difference was observed for 6-24 hours (6.3% vs. 7.7%). There were no differences in pain or in patient satisfaction.

Conclusions: After endoscopic thyroidectomy, total intravenous anesthesia with propofol-remifentanil is associated with less PONV during the early postoperative period (0-6 hours) than sevoflurane based balanced anesthesia.

Keywords: Endoscopic surgery; PONV; Thyroidectomy.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Systolic blood pressure and heart rate for the TIVA and BA groups. SBP: systolic blood pressure, HR: heart rate. *P < 0.05 between the groups.
See this image and copyright information in PMC

References

    1. Myles PS, Williams DL, Hendrata M, Anderson H, Weeks AM. Patient satisfaction after anesthesia and surgery: results of a prospective survey of 10,811 patients. Br J Anaesth. 2000;84:6–10. - PubMed
    1. Kovac AL. Prevention and treatment of postoperative nausea and vomiting. Drugs. 2000;59:213–243. - PubMed
    1. Koivuranta M, Läärä E, Snåre L, Alahuhta S. A survey of postoperative nausea and vomiting. Anaesthesia. 1997;52:443–449. - PubMed
    1. Cohen MM, Duncan PG, DeBoer DP, Tweed WA. The postoperative interview: assessing risk factors for nausea and vomiting. Anesth Analg. 1994;78:7–16. - PubMed
    1. Sonner JM, Hynson JM, Clark O, Katz JA. Nausea and vomiting following thyroid and parathyroid surgery. J Clin Anesth. 1997;9:398–402. - PubMed

LinkOut - more resources