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Editorial
. 2011 Aug;34(4):849-52.
doi: 10.1007/s10545-011-9370-0. Epub 2011 Jul 8.

How to find and diagnose a CDG due to defective N-glycosylation

Dirk J Lefeber, Eva Morava, Jaak Jaeken
Editorial

How to find and diagnose a CDG due to defective N-glycosylation

Dirk J Lefeber et al. J Inherit Metab Dis. 2011 Aug.
No abstract available

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Figures

Fig. 1
Fig. 1
Isofocusing techniques in the screening for CDG. a. Isofocusing of plasma transferrin for detection of N-glycosylation defects. Indicated is the most abundant glycan isoform of transferrin with two bi-antennary N-glycans, corresponding with tetrasialotransferrin. Lane 1: control, lane 2: CDG-I profile, lane 3: asialo type 2 profile, lane 4: disialo type 2 profile. b. Isofocusing of plasma apolipoprotein C3 for detection of mucin type O-glycosylation defects. Lane 1: control, lane 2: ApoC3-0 profile, lane 3: ApoC3-1 profile
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References

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