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. 1990;115(1-2):139-45.
doi: 10.1007/BF01310631.

Homology between feline herpesvirus-1 and canine herpesvirus

P A Rota  1 , R K Maes
Affiliations

Homology between feline herpesvirus-1 and canine herpesvirus

P A Rota et al. Arch Virol. 1990.

Abstract

The purpose of this study was to determine the extent of the relatedness between feline herpesvirus-1 (FHV-1) and canine herpesvirus (CHV). Immunoprecipitation studies using antisera to FHV-1 and CHV revealed that both share virion glycoprotein antigens with apparent molecular weights of approximately 60 and 68 kDa. Two non-glycosylated, virion-associated antigens of each virus also displayed weaker cross reactivity. Southern blot hybridization experiments indicated that restriction fragments which represented approximately 51% of the FHV-1 genome hybridized to CHV DNA under conditions which allowed less than 7% base pair mismatch. This is the first molecular characterization of cross-reactivity between FHV-1 and another herpesvirus.

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