Comment on

• Leptin administration does not prevent the bone mineral metabolism changes induced by weight loss.

  Conroy R, Girotra M, Shane E, McMahon DJ, Pavlovich KH, Leibel RL, Rosenbaum M, Korner J. Conroy R, et al. Metabolism. 2011 Sep;60(9):1222-6. doi: 10.1016/j.metabol.2011.02.010. Epub 2011 Apr 12. Metabolism. 2011. PMID: 21489573 Free PMC article. Clinical Trial.
• Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women.

  Sienkiewicz E, Magkos F, Aronis KN, Brinkoetter M, Chamberland JP, Chou S, Arampatzi KM, Gao C, Koniaris A, Mantzoros CS. Sienkiewicz E, et al. Metabolism. 2011 Sep;60(9):1211-21. doi: 10.1016/j.metabol.2011.05.016. Epub 2011 Jul 7. Metabolism. 2011. PMID: 21741057 Clinical Trial.