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. 2011 Sep;70(9):1523-5.
doi: 10.1136/ard.2011.151233. Epub 2011 Jul 7.

Bone mineral density and joint cartilage: four clinical settings of a complex relationship in osteoarthritis

Gabriel Herrero-Beaumont  1 , Jorge A Roman-Blas, Raquel Largo, Francis Berenbaum, Santos Castañeda
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Bone mineral density and joint cartilage: four clinical settings of a complex relationship in osteoarthritis

Gabriel Herrero-Beaumont et al. Ann Rheum Dis. 2011 Sep.

Abstract

Experimental and clinical data support the hypothesis that both high and low bone mineral density (BMD) conditions, including osteoporosis, may induce osteoarthritis. However, these conditions do not always predispose to osteoarthritis progression. Four clinical settings could arise from this relationship, and furthermore two phenotypes may be identified whether early osteoarthritis coexists with high or low BMD.

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