FoxO3 hastens autophagy and shrinks the heart but does not curtail pathological hypertrophy in adult mice
- PMID: 21742675
- PMCID: PMC3156910
- DOI: 10.1093/cvr/cvr196
FoxO3 hastens autophagy and shrinks the heart but does not curtail pathological hypertrophy in adult mice
Comment on
-
FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model.Cardiovasc Res. 2011 Sep 1;91(4):587-97. doi: 10.1093/cvr/cvr144. Epub 2011 May 30. Cardiovasc Res. 2011. PMID: 21628326
References
-
- Papanicolaou KN, Izumiya Y, Walsh K. Forkhead transcription factors and cardiovascular biology. Circ Res. 2008;102:16–31. doi:10.1161/CIRCRESAHA.107.164186. - DOI - PMC - PubMed
-
- Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, et al. Foxos are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell. 2007;128:309–323. doi:10.1016/j.cell.2006.12.029. - DOI - PMC - PubMed
-
- Schips TG, Wietelmann A, Höhn K, Schimanski S, Walther P, Braun T, et al. FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model. Cardiovasc Res. 2011;91:587–597. - PubMed
-
- Ronnebaum SM, Patterson C. The foxo family in cardiac function and dysfunction. Annu Rev Physiol. 2010;72:81–94. doi:10.1146/annurev-physiol-021909-135931. - DOI - PMC - PubMed
-
- Ferdous A, Battiprolu PK, Ni YG, Rothermel BA, Hill JA. Foxo, autophagy, and cardiac remodeling. J Cardiovasc Transl Res. 2010;3:355–364. doi:10.1007/s12265-010-9200-z. - DOI - PMC - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Research Materials
