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. 2011 Aug;22(8):463-4.
doi: 10.1258/ijsa.2011.010551. Epub 2011 Jul 8.

Herpes simplex virus type 2 seroprevalence and incidence in acute and chronic HIV-1 infection

M Lagnese  1 , E S Daar, P Christenson, G Rieg
Affiliations

Herpes simplex virus type 2 seroprevalence and incidence in acute and chronic HIV-1 infection

M Lagnese et al. Int J STD AIDS. 2011 Aug.

Abstract

Herpes simplex virus type 2 (HSV-2) HIV co-infection is common and associated with increased risk of HIV transmission. HSV-2 seroprevalence was assessed on stored samples from baseline and one year follow-up from 81 patients identified with acute HIV infection and 81 age-matched chronically infected men. HSV-2 seroprevalence at baseline was lower for those with acute rather than chronic HIV-infection, 51.9 versus 71.6% (P = 0.01); relative risk 0.72 (95% confidence interval [CI] 0.57-0.92). Since HSV-2 seroprevalence is lower in those newly HIV-infected, the diagnosis of early HIV infection may allow for counselling to reduce subsequent HSV-2 acquisition.

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