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Comparative Study
. 2012 Feb;285(2):331-7.
doi: 10.1007/s00404-011-1968-9. Epub 2011 Jul 9.

Comparative analysis of placental vasculature and placental volume in normal and IUGR pregnancies with the use of three-dimensional Power Doppler

Michal Pomorski  1 , Mariusz Zimmer, Jerzy Florjanski, Joanna Michniewicz, Artur Wiatrowski, Tomasz Fuchs, Ewa Milnerowicz-Nabzdyk
Affiliations
Comparative Study

Comparative analysis of placental vasculature and placental volume in normal and IUGR pregnancies with the use of three-dimensional Power Doppler

Michal Pomorski et al. Arch Gynecol Obstet. 2012 Feb.

Abstract

Objectives: To evaluate the differences in placental vascular indices and placental volume between normal and IUGR pregnancies.

Methods: A prospective study was conducted on a group of 100 normal and 20 IUGR pregnancies between 22 and 42 weeks of gestation. For the purpose of evaluation of placental volume and placental vascular indices, we applied 3D Power Doppler and VOCAL technique. Only patients with entirely visualized placenta were included in the study.

Results: A comparative analysis of vascularization index (VI), vascularization flow index (VFI), flow index (FI), and placental volume (PV) revealed statistically significant differences between normal and IUGR pregnancies. In normal pregnancies, the volume of the placenta was on average 92.42 cm(3) larger than in pregnancies complicated by IUGR. Receiver operating characteristic (ROC) curves were used to evaluate the clinical usefulness of placental vascular indices and placental volume for discriminating IUGR and normal pregnancies. It was concluded that the VI, VFI, PV, FI parameters are the best discriminants, with the cut-off values of 5.30, 2.30, 199, and 36.0, respectively.

Conclusions: The quantitative assessment of placental vasculature and placental volume by means of 3D Power Doppler and VOCAL technique is an adjunctive modality for differentiation between normal and IUGR pregnancies. Our findings further suggest that the vascularization index (VI) and vascularization flow index (VFI) are the best parameters with the most favorable discriminating potential for proper identification of IUGR pregnancies.

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Figures

Fig. 1
Fig. 1
Automatic calculation of VI, FI and VFI by 3D-Power Doppler Volume Histogram program
Fig. 2
Fig. 2
Comparison of placental volume in normal and IUGR pregnancies
Fig. 3
Fig. 3
Comparison of the ROC curves for VI, FI, VFI and PV indices in the IUGR pregnancies group
See this image and copyright information in PMC

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References

    1. Abramowicz JS, Sheiner E. In utero imaging of the placenta: importance for diseases of pregnancy. Placenta. 2007;28(Suppl A):14–22. doi: 10.1016/j.placenta.2007.02.004. - DOI - PubMed
    1. Abramowicz JS, Sheiner E. Ultrasound of the placenta: a systematic approach. Part I: imaging. Placenta. 2008;29:225–240. doi: 10.1016/j.placenta.2007.12.006. - DOI - PubMed
    1. Abramowicz JS, Sheiner E. Ultrasound of the placenta: a systematic approach. Part II: functional assessment (Doppler) Placenta. 2008;29:921–929. doi: 10.1016/j.placenta.2008.08.010. - DOI - PubMed
    1. de Paula CF, Ruano R, Campos JA, Zugaib M. Quantitative analysis of placental vasculature by three-dimensional Power Doppler ultrasonography in normal pregnancies from 12 to 40 weeks of gestation. Placenta. 2009;30:142–148. doi: 10.1016/j.placenta.2008.11.010. - DOI - PubMed
    1. Guiot C, Gaglioti P, Oberto M, Piccoli E, Rosato R, Todros T. Is three-dimensional Power Doppler ultrasound useful in the assessment of placental perfusion in normal and growth-restricted pregnancies? Ultrasound Obstet Gynecol. 2008;31(2):171–176. doi: 10.1002/uog.5212. - DOI - PubMed

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