Gastric adenocarcinoma in children and adolescents
- PMID: 21744476
- PMCID: PMC3137240
- DOI: 10.1002/pbc.23051
Gastric adenocarcinoma in children and adolescents
Abstract
Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.
Copyright © 2011 Wiley-Liss, Inc.
Conflict of interest statement
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References
-
- Harting MT, Blakely ML, Herzog CE, et al. Treatment issues in pediatric gastric adenocarcinoma. J Pediatr Surg. 2004;39(8):e8–10. - PubMed
-
- Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin. 2010;60(5):277–300. - PubMed
-
- Shah MA, Ramanathan RK, Ilson DH, et al. Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J Clin Oncol. 2006;24(33):5201–5206. - PubMed
-
- Kath R, Fiehler J, Schneider CP, et al. Gastric cancer in very young adults: apropos four patients and a review of the literature. J Cancer Res Clin Oncol. 2000;126(4):233–237. - PubMed
-
- McGill TW, Downey EC, Westbrook J, et al. Gastric carcinoma in children. J Pediatr Surg. 1993;28(12):1620–1621. - PubMed
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