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. 2011 Nov;16(11):1427-31.
doi: 10.1111/j.1365-3156.2011.02846.x. Epub 2011 Jul 12.

Evaluation of four rapid diagnostic tests for the diagnosis of Plasmodium vivax in Korea

Kyung Hee Kim  1 , Jin Woo Jang, Mi Kyung Woo, Jun Seo Oh, Eun Taek Han, Won Ja Lee, Seong Soo A An, Chae Seung Lim
Affiliations
Free article

Evaluation of four rapid diagnostic tests for the diagnosis of Plasmodium vivax in Korea

Kyung Hee Kim et al. Trop Med Int Health. 2011 Nov.
Free article

Abstract

Objective: To evaluate 4 rapid malaria diagnostic kits (RDTs) in Korea: OptiMAL test, SD BIOLINE Malaria Ag P.f/Pan test, Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test.

Methods: Hundred malaria patients with Plasmodium vivax (P. vivax) and 100 healthy volunteers were recruited. The results from earlier four RDTs were compared with the reference standard, the Giemsa-stained traditional microscopic diagnosis.

Results: Compared with the reference standard, the sensitivity and specificity for Plasmodium vivax were 92.7 and 100% for SD BIOLINE Malaria Ag P.f/Pan; and 94.6% and 100% for OptiMAL; 95.5% and 100% for both Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test.

Conclusion: The performances of all four malaria RDT kits were acceptable, although Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test gave superior performances with ROK isolates.

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