Polyarteritis nodosa presenting with frank hematuria
- PMID: 21749815
- PMCID: PMC3038379
- DOI: 10.5489/cuaj.973
Polyarteritis nodosa presenting with frank hematuria
Abstract
Polyarteritis nodosa (PAN) is an uncommon systemic vasculitis characterized by necrotizing inflammation of small- or medium-sized arteries. The disease normally presents with non-specific symptoms. Urological symptoms at presentation are extremely rare. We report a 65-year-old man who was diagnosed with a polyarteritis nodosa having presented atypically with left testicular pain and swelling, and an intratesticular lesion. He developed painless visible hematuria while under investigation. No gross arterio-venous fistula was seen to suggest a false aneurysm. Subsequently, laboratory studies showed positive anti-neutrophil cytoplasmic antibody levels and a raised erythrocyte sedimentation rate. This was an unusual presentation of PAN diagnosed with multidisciplinary input from the urology, radiology and nephrology teams.
Figures
References
-
- Kussmaul A, Maier R. Über eine bisher nicht beschriebene eigenthümliche Arterienerkrankung (Periarteritis nodosa), die mit Morbus Brightii und rapid fortschreitender, allgemeiner Muskellähmung einhergeht. Deutsches Archiv für klinische Medicin (Leipzig) 1866;1:484–518.
-
- Stanson AW, Friese JL, Johnson CM, et al. Polyarteritis nodosa: Spectrum of angiographic findings. Radiographics. 2001;21:151–9. - PubMed
-
- Hansell DM. Small-vessel diseases of the lung: CT-pathologic correlates. Radiology. 2002;225:639–53. - PubMed
-
- Guillevin L, Lhote F, Jarrousse B, et al. Polyarteritis nodosa related to hepatitis B virus. A retrospective study of 66 patients. Ann Med Interne (Paris) 1992;143(Suppl 1):63–74. - PubMed
LinkOut - more resources
Full Text Sources