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Clinical Trial
. 1990;240(1):1-4.
doi: 10.1007/BF02190083.

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial

M Maurer  1 , V Henn, A Dittrich, A Hofmann
Affiliations
Clinical Trial

Delta-9-tetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial

M Maurer et al. Eur Arch Psychiatry Clin Neurosci. 1990.

Abstract

A double-blind study was performed comparing 5 mg delta-9-tetrahydrocannabinol (THC) p.o., 50 mg codeine p.o., and placebo in a patient with spasticity and pain due to spinal cord injury. The three conditions were applied 18 times each in a randomized and balanced order. Delta-9-THC and codeine both had an analgesic effect in comparison with placebo. Only delta-9-THC showed a significant beneficial effect on spasticity. In the dosage of THC used no altered consciousness occurred.

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