Progesterone: not just a sex hormone anymore?
- PMID: 21760599
- DOI: 10.1038/ki.2011.131
Progesterone: not just a sex hormone anymore?
Abstract
The adrenal cortex synthesizes many steroids, but the mineralocorticoid aldosterone and the glucocorticoids cortisol and corticosteroid have been viewed as the principal steroids responsible for regulation of renal electrolyte excretion. A study by Elabida et al. challenges that paradigm and suggests that progesterone, classically viewed as a sex steroid, also participates in renal electrolyte balance.
Comment on
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Chronic potassium depletion increases adrenal progesterone production that is necessary for efficient renal retention of potassium.Kidney Int. 2011 Aug;80(3):256-62. doi: 10.1038/ki.2011.15. Epub 2011 Feb 16. Kidney Int. 2011. PMID: 21326170
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