Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Sep;16(2):97-102.
doi: 10.1007/BF01809293.

Estimation of epidermal growth factor receptor in 177 breast cancers: correlation with prognostic factors

M Bolla  1 , M Chedin, C Souvignet, J Marron, C Arnould, E Chambaz
Affiliations

Estimation of epidermal growth factor receptor in 177 breast cancers: correlation with prognostic factors

M Bolla et al. Breast Cancer Res Treat. 1990 Sep.

Abstract

Steroid receptors (ER, PR) and EGF-receptor were determined on 177 loco-regional primary breast cancers. Binding assay for EGF receptor was performed using a single saturating concentration of 125I-EGF incubated with membranes in the presence or absence of unlabeled EGF. With threshold values of 5 fmol/mg and 10 fmol/mg for EGF-R and steroid receptors respectively, we noted an inverse relationship between the expression of EGF-R, and ER and PR. EGF-R expression is decreased with tumor differentiation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Anticancer Res. 1988 Jan-Feb;8(1):173-6 - PubMed
    1. Breast Cancer Res Treat. 1988 May;11(2):173-8 - PubMed
    1. Breast Cancer Res Treat. 1987;9(3):191-9 - PubMed
    1. Cancer Res. 1984 Aug;44(8):3448-53 - PubMed
    1. Ann Endocrinol (Paris). 1984;45(6):412-3 - PubMed

Publication types

MeSH terms