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Review
. 2011 Jul;14(7):625-30.
doi: 10.3779/j.issn.1009-3419.2011.07.12.

[Gender-associated differences of lung cancer and mechanism]

[Article in Chinese]
Xin Xing  1 , Yongde Liao, Hexiao Tang, Guang Chen, Sheng Ju, Liangkun You
Affiliations
Review

[Gender-associated differences of lung cancer and mechanism]

[Article in Chinese]
Xin Xing et al. Zhongguo Fei Ai Za Zhi. 2011 Jul.

Abstract
in English, Chinese

Lung cancer has been viewed as the most common malignant cancer with high incidence, mortality and poor survival all over the world. A lot of investigations indicated there are significant gender-associated differences in lung cancer in several characteristics such as epidemiology, pathology, clinical outcome and prognosis. The insight into these differences may help to clarify the gender-associated characteristics of lung cancer, and to drawn out new approach for treatment and prevent of lung cancer depending on gender-associated characteristics. Furthermore, study on mechanism of gender-associated characteristics may even help to illuminate the pathogenesis of lung cancer.

肺癌是全球发病率、死亡率最高、治疗效果差的恶性肿瘤。肺癌在流行病学、病理类型、疗效和预后、甚至发病机制等多方面均表现出明显性别差异。对这些差异的深入剖析能更好地认识男女性别肺癌各自的特点，为肺癌防治采用不同的性别化措施提供新线索和思路；而对导致性别差异的具体机制进行深入研究，有助于阐明肺癌的发病机制。

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