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Case Reports
. 2011 Jul-Aug;33(4):412.e1-3.
doi: 10.1016/j.genhosppsych.2011.03.011. Epub 2011 May 5.

Hoofbeats and zebras: neurodegenerative disorder presenting as a "first episode" of psychosis

Banu Ozkan  1 , Vivek Phutane, Elizabeth Jonas, Cenk Tek, Vinod Srihari
Affiliations
Case Reports

Hoofbeats and zebras: neurodegenerative disorder presenting as a "first episode" of psychosis

Banu Ozkan et al. Gen Hosp Psychiatry. 2011 Jul-Aug.

Abstract

Neurodegenerative disorders can include diverse neuropsychiatric symptoms. Here we present a case referred to a "first-episode" psychosis clinic with socio-occupational decline, auditory hallucinations and paranoid ideation who subsequently exhibited a rapid, severe cognitive and behavioral decline. The brain magnetic resonance imaging findings of the patient have shown a progressive cortical atrophy prominent in the frontal lobes due to a neurodegenerative disorder.

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Figures

Figure 1
Figure 1
A, B. An interval of 15 months between two imaging studies (A; the first repeat MRI, B; the second repeat MRI) showed a significant worsening in the cerebral volume loss prominent in the frontal lobes.
See this image and copyright information in PMC

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