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. 2011 Sep 1;17(17):5559-61.
doi: 10.1158/1078-0432.CCR-10-2051. Epub 2011 Jul 15.

Optimizing chemotherapy-free survival for the ER/HER2-positive metastatic breast cancer patient

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Optimizing chemotherapy-free survival for the ER/HER2-positive metastatic breast cancer patient

Stefan Glück et al. Clin Cancer Res. .

Abstract

The recent incremental advances made in the treatment of metastatic breast cancer have elicited potential for survival extension in this treatable, yet incurable, population of breast cancer patients. Clinicians have focused on targeted therapies, which aim at signaling receptors such as the human epidermal receptor superfamily, the estrogen receptor, VEGF, the insulin-like growth factor receptor, the hepatocyte growth factor receptor (cMET), phosphoinositide 3-kinase, mTOR, and many others.

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