Poliovirus antibody in children from a paediatric hospital in Ibadan, Nigeria

Abstract

The immune status of 100 Nigerian children (ages 0-14) from a paediatric hospital in Ibadan, against poliovirus, after the administration of polyvalent oral poliovirus vaccine (types 1, 2 and 3) was determined using serum neutralisation test. High antibody titres were demonstrated in 78% of all the age groups tested. 57% of children under two years of age, 75% of those three to five years, and 100% of those above six years, had high poliovirus antibodies. 77% of male (47 out of 61) and 79% of female (31 out of 39) were positive. The difference between the sexes is not statistically significant (P greater than 0.05).