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Comparative Study
. 1990 Dec 15;96(2):177-80.
doi: 10.1016/0378-1119(90)90250-u.

Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases

N P Schultes  1 , A D Ellington, J M Cherry, J W Szostak
Affiliations
Comparative Study

Saccharomyces cerevisiae homoserine kinase is homologous to prokaryotic homoserine kinases

N P Schultes et al. Gene. .

Abstract

The Saccharomyces cerevisiae gene (THR1) encoding homoserine kinase (HK; EC 2.7.1.39) was cloned by complementation in yeast. Disruption of the THR1 gene results in threonine auxotrophy in yeast. Comparison of the amino acid sequences of yeast and bacterial HKs reveals substantial similarity.

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