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Case Reports
. 2011 Aug;118(2 Pt 2):445-449.
doi: 10.1097/AOG.0b013e3182161828.

Placental mesenchymal dysplasia presenting as a twin gestation with complete molar pregnancy

Roman Starikov  1 , Randi Goldman, Don S Dizon, Stefan Kostadinov, Stephen Carr
Affiliations
Case Reports

Placental mesenchymal dysplasia presenting as a twin gestation with complete molar pregnancy

Roman Starikov et al. Obstet Gynecol. 2011 Aug.

Abstract

Background: Placental mesenchymal dysplasia is a rare abnormality characterized by placentomegaly, grapelike cystic vesicles, and villous hyperplasia. The clinical and ultrasonographic presentation may mimic molar pregnancy, provoking incorrect diagnoses and unnecessary therapeutic interventions.

Case: A 36-year-old nulliparous woman presented for prenatal ultrasonography that indicated the presence of one gestational sac containing both fetus and cystic mass, concerning for partial molar pregnancy. Amniocentesis returned a 46,XX karyotype, suggesting a twin gestation with complete mole. The patient was monitored closely and, because of fetal growth restriction, was induced successfully at term and delivered a healthy newborn. Histopathologic findings of the placenta were consistent with placental mesenchymal dysplasia.

Conclusion: Although placental mesenchymal dysplasia is often confused with molar pregnancy, it is important to consider both in a differential to avoid inappropriate treatments.

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References

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