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. 2011 Apr;4(2):222-32.
doi: 10.4103/0974-2700.82210.

Physiopathology of shock

Fabrizio Giuseppe Bonanno  1
Affiliations

Physiopathology of shock

Fabrizio Giuseppe Bonanno. J Emerg Trauma Shock. 2011 Apr.

Abstract

SHOCK SYNDROMES ARE OF THREE TYPES: cardiogenic, hemorrhagic and inflammatory. Hemorrhagic shock has its initial deranged macro-hemodynamic variables in the blood volume and venous return. In cardiogenic shock there is a primary pump failure that has cardiac output/mean arterial pressure as initial deranged variables. In Inflammatory Shock it is the microcirculation that is mainly affected, while the initial deranged macrocirculation variable is the total peripheral resistance hit by systemic inflammatory response.

Keywords: Physiology; physiopathology; shock.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Primary variable derangement in abnormal macrocirculation
Scheme 1
Scheme 1
Variables interaction in reversible HS
Scheme 2
Scheme 2
Variables interaction in reversible CS
Scheme 3
Scheme 3
Variables interaction in reversible IS
Figure 2
Figure 2
Clinical correlates and timing of occurrence of the microcirculation disorders in sepsis
Figure 3
Figure 3
Microcirculation disorders in sepsis effects of the damage by lps and other toxins
Appendix A
Appendix A
Correlation between macro-hemodynamic and biochemical vital functions and factors
Appendix B
Appendix B
The four acute life-saving and maintaining hemodynamic reflexes
Appendix C
Appendix C
Effects of the inflammatory mediators
See this image and copyright information in PMC

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