doi: 10.1046/j.1468-2982.1990.1005207.x.
Lack of antinociceptive activity of sumatriptan in rodents
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- PMID: 2176936
- DOI: 10.1046/j.1468-2982.1990.1005207.x
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Lack of antinociceptive activity of sumatriptan in rodents
Cephalalgia.
1990 Oct.
Abstract
The present study attempts to determine whether the novel anti-migraine drug sumatriptan has antinociceptive activity in rodents. Sumatriptan had little or no antinociceptive activity against a range of noxious stimuli and we therefore conclude that it is unlikely that the beneficial effects of the drug in treating migraine are due to a non-specific analgesic action.
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