Transgenic mouse models and prion strains
- PMID: 21769720
- DOI: 10.1007/128_2011_166
Transgenic mouse models and prion strains
Abstract
Here we review the known strain profiles of various prion diseases of animals and humans, and how transgenic mouse models are being used to elucidate basic molecular mechanisms of prion propagation and strain variation and for assessing the zoonotic potential of various animal prion strains.
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