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Review
. 2011:305:79-99.
doi: 10.1007/128_2011_166.

Transgenic mouse models and prion strains

Affiliations
Review

Transgenic mouse models and prion strains

Glenn C Telling. Top Curr Chem. 2011.

Abstract

Here we review the known strain profiles of various prion diseases of animals and humans, and how transgenic mouse models are being used to elucidate basic molecular mechanisms of prion propagation and strain variation and for assessing the zoonotic potential of various animal prion strains.

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