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. 2011 Jul 19:5:318.
doi: 10.1186/1752-1947-5-318.

Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report

Kristin Coners  1 , Scott E Woods, Michael Webb
Affiliations

Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report

Kristin Coners et al. J Med Case Rep. .

Erratum in

Abstract

Introduction: We describe the case of a patient with small cell lung cancer and dual paraneoplastic syndromes involving adrenocorticotropic hormone and calcitonin. To the best of our knowledge, dual paraneoplastic syndromes involving these two hormones have not been previously reported in the literature.

Case presentation: A 74-year-old Caucasian woman presented with a left hilar mass and metastatic disease in the liver and right adrenal gland. The patient complained only of intermittent diarrhea. Her laboratory values exhibited metabolic alkalosis with hypokalemia, hypocalcemia, hypomagnesemia, hypophosphatemia, and hyperglycemia.

Conclusion: We discuss the work-up and treatment of the patient's unusual laboratory presentation with two concurrent paraneoplastic syndromes.

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References

    1. Gropp C, Havemann K, Scheuer A. Ectopic hormones in lung cancer patients at diagnosis and during therapy. Cancer. 1980;46:347–354. doi: 10.1002/1097-0142(19800715)46:2<347::AID-CNCR2820460223>3.0.CO;2-S. - DOI - PubMed
    1. Suzuki H, Tsutsumi Y, Yamaguchi K, Abe K, Yokoyama T. Small cell lung carcinoma with ectopic adrenocorticotropic hormone and antidiuretic hormone syndromes: a case report. Jpn J Clin Oncol. 1984;14:129–137. - PubMed
    1. Shaker JL, Brickner RC, Divgi AB, Raff H, Findling JW. Case report: renal phosphate wasting, syndrome of inappropriate antidiuretic hormone, and ectopic corticotropin production in small cell carcinoma. Am J Med Sci. 1995;310:38–41. doi: 10.1097/00000441-199507000-00011. - DOI - PubMed
    1. Pierce ST, Metcalfe M, Banks ER, O'Daniel ME, DeSimone P. Small cell carcinoma with two paraendocrine syndromes. Cancer. 1992;69:2258–2261. doi: 10.1002/1097-0142(19920501)69:9<2258::AID-CNCR2820690908>3.0.CO;2-5. - DOI - PubMed
    1. Castro Cabezas M, Vrinten DH, Burgers JA, Croughs RJ. Central diabetes insipidus and Cushing's syndrome due to ectopic ACTH production by disseminated small cell lung cancer: a case report. Neth J Med. 1998;53:32–36. doi: 10.1016/S0300-2977(98)00051-5. - DOI - PubMed

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