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. 2009 Mar;14(2):123-7.

Primary Percutaneous Coronary Intervention (PPCI) in acute myocardial infarction complicated with cardiogenic shock in a newly emerging cardiac center in Nepal

Affiliations

Primary Percutaneous Coronary Intervention (PPCI) in acute myocardial infarction complicated with cardiogenic shock in a newly emerging cardiac center in Nepal

Arun Maskey et al. J Res Med Sci. 2009 Mar.

Abstract

Background: Acute myocardial infarction (AMI) is complicated by cardiogenic shock in 7~10% of patients. Mortality rate is exceedingly high and reaches 70-80% in those treated conservatively. Large thrombolytic trials demonstrate 60% mortality with most effective thrombolytic agent.

Methods: In between September 2005 to August 2008 total PCI in Shahid Gangalal National Heart Center (SGNHC) in Nepal was 452. Among them primary PCI (PPCI) in AMI with cardiogenic shock was done in only 16 patients (3.5%).

Results: This study showed in-hospital mortality of 50% (n = 8). Of 50% (n = 8) alive patients with cardiogenic shock who underwent PPCI, 6 patients are in routine follow-up over 12 months and 2 were doing well in subsequent 6 months but not in follow up after that.

Conclusion: Primary PCI in AMI complicated by cardiogenic shock has lower mortality and improved outcome. High cost, high in-hospital mortality and lack of trained personnel are major limitations.

Keywords: Primary percutaneous coronary intervention; SGNHC (Shahid Gangalal National Heart Center); acute myocardial infarction; cardiogenic shock.

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Conflict of interest statement

Conflict of Interest

Authors have no conflicts of interest.

References

    1. Hasdai D, Topol EJ, Califf RM, Berger PB, Holmes DR., Jr Cardiogenic shock complicating acute coronary syndromes. Lancet. 2000;356(9231):749–56. - PubMed
    1. Goldberg RJ, Samad NA, Yarzebski J, Gurwitz J, Bigelow C, Gore JM. Temporal trends in cardiogenic shock complicating acute myocardial infarction. N Engl J Med. 1999;340(15):1162–8. - PubMed
    1. Hasdai D, Holmes DR, Jr, Topol EJ, Berger PB, Criger DA, Hochman JS, et al. Frequency and clinical outcome of cardiogenic shock during acute myocardial infarction among patients receiving reteplase or alteplase. Results from GUSTO-III. Global Use of Strategies to Open Occluded Coronary Arteries. Eur Heart J. 1999;20(2):128–35. - PubMed
    1. Sanborn TA, Sleeper LA, Bates ER, Jacobs AK, Boland J, French JK, et al. Impact of thrombolysis, intraaortic balloon pump counterpulsation, and their combination in cardiogenic shock complicating acute myocardial infarc-tion: a report from the SHOCK Trial Registry.SHould we emergently revascularize Occluded Coronaries for cardiogenic shocK? J Am Coll Cardiol. 2000;36(3 Suppl A):1123–9. - PubMed
    1. Silber S, Albertsson P, Aviles FF, Camici PG, Colombo A, Hamm C, et al. Guidelines for percutaneous coronary interventions.The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology. Eur Heart J. 2005;26(8):804–47. - PubMed

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