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Case Reports
. 2009 Nov;14(6):385-7.

Sister Mary Joseph nodule-A case report with review of literature

Ishrat Hussain Dar  1 , Mqtasid Ahmed Kamili, Showkat Hussain Dar, Faiz Ahmed Kuchaai
Affiliations
Case Reports

Sister Mary Joseph nodule-A case report with review of literature

Ishrat Hussain Dar et al. J Res Med Sci. 2009 Nov.

Abstract

Sister Mary Joseph nodule or Sister Mary Joseph Sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. A rare case of Sister Mary Joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same.

Keywords: FNAC; Metastasis; Umbilical Nodule.

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Conflict of interest statement

Conflict of Interests:

Authors have no conflict of interests.

Figures

Figure 1
Figure 1
A visible periumblical bluish violet swelling suggestive of a Sister Mary Joseph nodule
Figure 2
Figure 2
Metastatic deposits of a well differentiated adenocarcinoma documented by FNAC
See this image and copyright information in PMC

References

    1. Steck WD, Helwig EB. Tumors of the umbilicus. Cancer. 1965;18(7):907–15. - PubMed
    1. Urbano FL. Sister Joseph's nodule. (44).Hospital Physician. 2001;37(5):33–5.
    1. Larentzakis A, Theodorou D, Fili K, Manataki A, Bizimi V, Tibishrani M, et al. Sister Mary Joseph's nodule: three case reports. Cases Journal. 2008;1:182. - PMC - PubMed
    1. Galvan VG. Sister Mary Joseph's nodule. Ann Intern Med. 1998;128(5):410. - PubMed
    1. Majumdar B, Wiskind AK, Croft BN, Dudley AG. The Sister (Mary) Joseph nodule: its significance in gynecology. Gynecol Oncol. 1991;40(2):152–9. - PubMed

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