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. 2011 Sep;159(3):504-6.
doi: 10.1016/j.jpeds.2011.05.021. Epub 2011 Jul 21.

Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders

Rachel Rosen  1 , Nikki Johnston, Kristen Hart, Umakanth Khatwa, Eliot Katz, Samuel Nurko
Affiliations

Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders

Rachel Rosen et al. J Pediatr. 2011 Sep.

Abstract

The aim of the study was to determine if children with chronic cough or wheezing and with more full-column, nonacid reflux have a higher likelihood of a positive bronchoalveolar lavage fluid culture. In a prospective study of 46 children with cough who were undergoing endoscopy, multichannel intraluminal impedance testing, and bronchoscopy, we found that patients who had a positive culture had significantly more full-column, nonacid gastroesophageal reflux than those who had a negative culture.

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Conflict of interest statement

The authors declare no conflicts of interest.

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References

    1. Canani RB, Cirillo P, Roggero P, Romano C, Malamisura B, Terrin G, et al. Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics. 2006;117:e817–e820. - PubMed
    1. Laheij RJ, Sturkenboom MC, Hassing RJ, Dieleman J, Stricker BH, Jansen JB. Risk of community-acquired pneumonia and use of gastric acid-suppressive drugs. Jama. 2004;292:1955–1960. - PubMed
    1. Rosen R, Fritz J, Nurko A, Simon D, Nurko S. Lipid-laden macrophage index is not an indicator of gastroesophageal reflux-related respiratory disease in children. Pediatrics. 2008;121:e879–e884. - PMC - PubMed
    1. Johnston N, Knight J, Dettmar PW, Lively MO, Koufman J. Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease. Laryngoscope. 2004;114:2129–2134. - PubMed
    1. Colombo JL, Hallberg TK. Recurrent aspiration in children: lipid-laden alveolar macrophage quantitation. Pediatr Pulmonol. 1987;3:86–89. - PubMed

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