Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jun;7(2):105-6.
doi: 10.3988/jcn.2011.7.2.105. Epub 2011 Jun 28.

Melanotic choroid plexus carcinoma of the posterior fossa

Kalpalata Tripathy  1 , Aparijita Misra, Debiprasad Misra, Sujata Pujari, Manjushree Nayak, Jayshree Rath
Affiliations

Melanotic choroid plexus carcinoma of the posterior fossa

Kalpalata Tripathy et al. J Clin Neurol. 2011 Jun.

Abstract

Background: The pigmented or melanotic variant of choroid plexus carcinoma is very rarely encountered.

Case report: We report herein a case of melanotic or pigmented choroid plexus carcinoma in the posterior fossa of an 11-year-old female.

Conclusions: A histopathological study supported by immunohistochemistry helped the authors to diagnose this rare entity. How to differentiate this tumor from pigmented papillary medulloblastoma, cerebellar papillary ependymoma, and metastatic malignant melanoma is discussed.

Keywords: HMB-45; choroid plexus carcinoma; melanin; posterior fossa.

PubMed Disclaimer

Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Contrast-enhanced computed tomography scan revealing a large heterogeneous mass in the posterior fossa extending into the fourth ventricle.
Fig. 2
Fig. 2
Photomicrograph showing pigmented tumor cells in a papillary pattern, with a few tubules and focal solid areas (hematoxylin and eosin stain, ×100).
See this image and copyright information in PMC

References

    1. Lana-Peixoto MA, Lagos J, Silbert SW. Primary pigmented carcinoma of the choroid plexus. A light and electron microscopic study. J Neurosurg. 1977;47:442–450. - PubMed
    1. Dohrmann GJ, Collias JC. Choroid plexus carcinoma. J Neurosurg. 1975;43:225–232. - PubMed
    1. Boesel CP, Suhan JP. A pigmented choroid plexus carcinoma: histochemical and ultrastructural studies. J Neuropathol Exp Neurol. 1979;38:177–186. - PubMed
    1. Barreto AS, Vassallo J, Queiroz Lde S. Papillomas and carcinomas of the choroid plexus: histological and immunohistochemical studies and comparison with normal fetal choroid plexus. Arq Neuropsiquiatr. 2004;62:600–607. - PubMed
    1. Yamazaki S, Ito U, Tomita H, Takada Y, Inaba Y, Okeda R. [Melanosis of choroid plexus papilloma of the lateral ventricle: a case report] No Shinkei Geka. 1987;15:1033–1037. - PubMed