Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Dec;41(12):1578-82.
doi: 10.1007/s00247-011-2205-1. Epub 2011 Jul 21.

Prospective motion correction improves diagnostic utility of pediatric MRI scans

Affiliations

Prospective motion correction improves diagnostic utility of pediatric MRI scans

Joshua M Kuperman et al. Pediatr Radiol. 2011 Dec.

Abstract

A new technique for prospectively correcting head motion (called PROMO) during acquisition of high-resolution MRI scans has been developed to reduce motion artifacts. To evaluate the efficacy of PROMO, four T1-weighted image volumes (two with PROMO enabled, two uncorrected) were acquired for each of nine children. A radiologist, blind to whether PROMO was used, rated image quality and artifacts on all sagittal slices of every volume. These ratings were significantly better in scans collected with PROMO relative to those collected without PROMO (Mann-Whitney U test, P < 0.0001). The use of PROMO, especially in motion-prone patients, should improve the accuracy of measurements made for clinical care and research, and potentially reduce the need for sedation in children.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Examples of image quality ratings provided by a clinical radiologist. The slice rating is shown in the top left corner of each representative image
Fig. 2
Fig. 2
Number of images rated at each quality level with PROMO on and PROMO off
Fig. 3
Fig. 3
Single sagittal slice from each T1-W scan of the three children with the largest measured in-scan motion. Columns 1 and 2 were acquired with PROMO off and columns 3 and 4 were acquired with PROMO on

References

    1. Hubbard A, Markowitz RI, Kimmel B, et al. Sedation for pediatric patients undergoing CT and MRI. J Comput Assist Tomogr. 1992;16:3–6. - PubMed
    1. Sanborn P, Michna E, Zurakowski D, et al. Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology. 2005;237:288–294. - PubMed
    1. Shankaranarayanan A, Roddey C, White NS, et al. Motion insensitive 3D imaging using a novel real-time image-based 3D PROspective MOtion Correction Method (3D PROMO) ISMRM; Germany: 2007.
    1. Brown TT, Kuperman JM, Erhart MJ, et al. Prospective motion correction of high-resolution magnetic resonance imaging data in children. Neuroimage. 2010;53:139–145. - PMC - PubMed
    1. Gelb A. Applied optimal estimation. MIT; Cambridge: 1974.

Publication types