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Review
. 2011 Oct;57(1):73-88.
doi: 10.1111/j.1600-0757.2011.00386.x.

Squamous cell carcinoma and precursor lesions: diagnosis and screening in a technical era

Catherine F Poh, Calum E MacAulay, Denise M Laronde, P Michele Williams, Lewei Zhang, Miriam P Rosin
Review

Squamous cell carcinoma and precursor lesions: diagnosis and screening in a technical era

Catherine F Poh et al. Periodontol 2000. 2011 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Assessment of a dynamic field at risk
Figure 2
Figure 2
Clinical questions in oral cancer control in screening and diagnosis
Figure 3
Figure 3. The use of FV during follow-up for detection of cancer recurrence
A 42-year-old male nonsmoker was examined 4 years after surgery and radiation therapy for Stage III squamous cell carcinoma involving the left lateral tongue and left cervical lymph nodes. A. White light image of a well-healed scar at left lateral tongue with no clinically visible lesion (arrow); B. The same area (arrow) under FV showing a dark brown FVL. The comparative biopsy from the FVL area 4-and-half years after initial treatment showed severe epithelial dysplasia. The area posterior to the FVL showed FVR representing a well-healed scar (star).
Figure 4
Figure 4. The use of FV to identify a distant lesion during follow-up
A 68-year-old female smoker presented with a carcinoma in situ on the left anterior ventral tongue after completion of an excisional biopsy with margin positive for mild epithelial dysplasia. At 3 months post surgery, she was referred for the assessment of the surgical site. A. White light image showing a scar without clinically visible lesion on left anterior ventral tongue (arrow); B. FV image showing some FVL area (arrow). C. White light image showing an ill-defined mildly erythematous area at left posterior soft palate and FV image showing a well-defined dark brown FVL area (D, arrow) 8 cm distant to the initial cancer site. The biopsy showed carcinoma in situ.
Figure 5
Figure 5. Demarcation of dysplastic lesion with 405 nm excitation
A 55-year-old female former smoker presented with a pathology-proven severe epithelial dysplasia at the anterior of floor of mouth extending to the lingual frenum. A. White light image showing an ill-defined, slightly erythematous lesion (arrow) at anterior of mouth; B. FV image showing a well-demarcated area of FVL area (arrow).
See this image and copyright information in PMC

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