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Comment
. 2011 Jul 26;21(14):R542-3.
doi: 10.1016/j.cub.2011.06.026.

Gene regulation: piecing together the puzzle of enhancer evolution

Rhea R Datta  1 , Stephen Small
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Free article
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Gene regulation: piecing together the puzzle of enhancer evolution

Rhea R Datta et al. Curr Biol. .
Free article

Abstract

The sequences of some gene regulatory elements diverge considerably, even between closely related species. A detailed analysis of the fast-evolving sparkling enhancer in Drosophila now identifies key compensatory mechanisms and 'grammar' elements that are critical for maintaining functional integrity.

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