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. 2012 Mar-Apr;28(3):222-5.
doi: 10.1097/AJP.0b013e318227ce7a.

Phantom limb pain in young cancer-related amputees: recent experience at St Jude children's research hospital

Laura L Burgoyne  1 , Catherine A Billups, José L Jirón Jr, Roland N Kaddoum, Becky B Wright, George B Bikhazi, Mary Edna Parish, Lilia A Pereiras
Affiliations

Phantom limb pain in young cancer-related amputees: recent experience at St Jude children's research hospital

Laura L Burgoyne et al. Clin J Pain. 2012 Mar-Apr.

Abstract

Objectives: This study in children and young adults having cancer-related amputation aimed to examine the incidence of phantom limb pain (PLP) in the first year after amputation and also the proportion of patients who had preamputation pain.

Methods: A retrospective review of medical records was undertaken. The proportion of patients with PLP was reported. Fisher exact test was used to examine the association between PLP and the presence of preamputation pain and between PLP and age (≤ 18 y vs. >18 y).

Results: Twenty-six amputations were performed on 25 patients. During the year after amputation, 76% of patients had experienced PLP at some time. After 1 year, though, only 10% still had PLP. Preamputation pain was present in 64% of patients. Although both of our patients with PLP at 1 year were young adults (older than or equal to 18 y) and both had preamputation pain, we found no statistically significant associations between age or the presence of preamputation pain with PLP.

Discussion: PLP after cancer-related amputation in children and young adults seems to be common but generally short lived in most patients.

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Figures

Figure 1a
Figure 1a
Numbers of patients with PLP by time point in the subset of patients with pre-amputation pain
Figure 1b
Figure 1b
Numbers of patients with PLP by time point in the subset of patients without pre-amputation pain
See this image and copyright information in PMC

References

    1. Nikolajsen L, Jensen TS. Phantom limb pain. Br J Anaesth. 2001;87:107–116. - PubMed
    1. Wilkins KL, McGrath PJ, Finley GA, et al. Phantom limb sensations and phantom limb pain in child and adolescent amputees. Pain. 1998;78:7–12. - PubMed
    1. Smith J, Thompson JM. Phantom limb pain and chemotherapy in pediatric amputees. Mayo Clin Proc. 1995;70:357–364. - PubMed
    1. Krane EJ, Heller LB. The prevalence of phantom sensation and pain in pediatric amputees. J Pain Symptom Manage. 1995;10:21–29. - PubMed
    1. Boyle M, Tebbi CK, Mindell ER, et al. Adolescent adjustment to amputation. Med Pediatr Oncol. 1982;10:301–312. - PubMed

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