Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1990 Apr 1;65(7):1533-7.
doi: 10.1002/1097-0142(19900401)65:7<1533::aid-cncr2820650714>3.0.co;2-l.

Change in a complex translocation involving band 7q34 and 9p- in a case of T-cell lymphoblastic lymphoma

K Ohyashiki  1 , A Iwabuchi, H Fujieda, A Suzuki, M Nakano, J H Ohyashiki, K Toyama, H Serizawa, R Amemiya, Y Hayata
Affiliations
Review

Change in a complex translocation involving band 7q34 and 9p- in a case of T-cell lymphoblastic lymphoma

K Ohyashiki et al. Cancer. .

Abstract

The authors report a case of T-cell type non-Hodgkin's lymphoma (NHL) in which neoplastic cells possessed a three-way translocation involving chromosomal bands 3q21, 7q34, and 22q11, as well as partial monosomy of the short arm of chromosome 9. In the literature, most reported cases of 7q32-q36 abnormalities had T-cell type leukemia/lymphoma and were younger than 20 years. Two NHL cases, including the current case, were diagnosed as having lymphoblastic lymphoma with a leukemic transformation. The neoplastic cells of the reported cases commonly showed CD2 (E-rosette receptors) and CD38. All 17 patients but three manifested a mediastinal mass at diagnosis and seven had central nervous system lesions or pleural infiltration. Furthermore, five of the 19 reported cases also showed 9p- change.

PubMed Disclaimer

LinkOut - more resources