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Review
. 2011 Nov-Dec;29(6):860-8.
doi: 10.1016/j.biotechadv.2011.07.003. Epub 2011 Jul 20.

Application of chicken egg yolk immunoglobulins in the control of terrestrial and aquatic animal diseases: a review

Yongping Xu  1 , Xiaoyu Li, Liji Jin, Yuhong Zhen, Yanan Lu, Shuying Li, Jiansong You, Linhui Wang
Affiliations
Review

Application of chicken egg yolk immunoglobulins in the control of terrestrial and aquatic animal diseases: a review

Yongping Xu et al. Biotechnol Adv. 2011 Nov-Dec.

Abstract

Oral administration of chicken egg yolk immunoglobulin (IgY) has attracted considerable attention as a means of controlling infectious diseases of bacterial and viral origin. Oral administration of IgY possesses many advantages compared with mammalian IgG including cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of terrestrial and aquatic animal diseases and speculates on the future of IgY technology. Included are a review of the potential application of IgY for the treatment of livestock diseases such as mastitis and diarrhea, poultry diseases such as Salmonella, Campylobacteriosis, infectious bursal disease and Newcastle disease, as well as aquatic diseases like shrimp white spot syndrome virus, Yersina ruckeri and Edwardsiella tarda. Some potential obstacles to the adoption of IgY technology are also discussed.

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Figures

Fig. 1
Fig. 1
Structure of IgG and IgY.
Fig. 2
Fig. 2
Effect of IgY on the survival rate of shrimp challenged with white spot syndrome virus.
See this image and copyright information in PMC

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