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Comparative Study
. 1990 Mar;9(3):965-70.
doi: 10.1002/j.1460-2075.1990.tb08195.x.

A tripartite HIV-1 tat-env-rev fusion protein

J Salfeld  1 , H G Göttlinger, R A Sia, R E Park, J G Sodroski, W A Haseltine
Affiliations
Comparative Study

A tripartite HIV-1 tat-env-rev fusion protein

J Salfeld et al. EMBO J. 1990 Mar.

Abstract

A 26 kd protein reactive with antiserum to the transactivator tat of the Human Immunodeficiency Virus Type 1 (HIV-1) has been detected in virus producing cells. The 26 kd protein is shown to be a tripartite fusion protein including coding sequences of the tat, envelope (env) and regulator of virion expression (rev) genes. Fusion of these coding sequences occurs by use of a previously undescribed exon within env. This 26 kd protein, designated tnv, has tat but no rev activity detectable with the assay used. The existence of other less abundant tat and rev related proteins in HIV-1 producing cells is also noted.

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References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. Cell. 1989 Sep 8;58(5):901-10 - PubMed
    1. Nucleic Acids Res. 1982 Jan 22;10(2):459-72 - PubMed
    1. Mol Cell Biol. 1982 Sep;2(9):1044-51 - PubMed
    1. Gene. 1983 Nov;25(2-3):263-9 - PubMed

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