Time for a gut check: evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome

doi:10.1002/art.30558

. 2011 Nov;63(11):3195-8.

doi: 10.1002/art.30558.

Time for a gut check: evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome

James T Rosenbaum¹, Michael P Davey

Affiliations

PMID: 21792826
PMCID: PMC3204318
DOI: 10.1002/art.30558

Time for a gut check: evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome

James T Rosenbaum et al. Arthritis Rheum. 2011 Nov.

. 2011 Nov;63(11):3195-8.

doi: 10.1002/art.30558.

Authors

James T Rosenbaum¹, Michael P Davey

Affiliation

¹ Oregon Health & Science University, Portland, OR, USA. rosenbaj@ohsu.edu

PMID: 21792826
PMCID: PMC3204318
DOI: 10.1002/art.30558

No abstract available

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Comment in

The intestinal microbiome in ankylosing spondylitis: comment on the article by Rosenbaum and Davey.
Highton J, Stebbings S, Jenks K. Highton J, et al. Arthritis Rheum. 2012 Feb;64(2):597-8; author reply 598. doi: 10.1002/art.33406. Arthritis Rheum. 2012. PMID: 21987359 No abstract available.

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References

1. Brewerton DA, Hart FD, Nicholls A, Caffrey M, James DC, Sturrock RD. Ankylosing spondylitis and HL-A 27. Lancet. 1973;1:904–7. - PubMed
1. Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973;288:704–6. - PubMed
1. Taurog JD. The role of HLA-B27 in spondyloarthritis. J Rheumatol. 2010;37:2606–16. - PubMed
1. Mielants H, Veys EM, Cuvelier C, De Vos M, Botelberghe L. HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol. 1985;12:294–8. - PubMed
1. Friswell M, Campbell B, Rhodes J. The role of bacteria in the pathogenesis of inflammatory bowel disease. Gut and liver. 2010;4:295–306. - PMC - PubMed

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[1] Brewerton DA, Hart FD, Nicholls A, Caffrey M, James DC, Sturrock RD. Ankylosing spondylitis and HL-A 27. Lancet. 1973;1:904–7. - PubMed

[2] Brewerton DA, Hart FD, Nicholls A, Caffrey M, James DC, Sturrock RD. Ankylosing spondylitis and HL-A 27. Lancet. 1973;1:904–7. - PubMed

[3] Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973;288:704–6. - PubMed

[4] Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med. 1973;288:704–6. - PubMed

[5] Taurog JD. The role of HLA-B27 in spondyloarthritis. J Rheumatol. 2010;37:2606–16. - PubMed

[6] Taurog JD. The role of HLA-B27 in spondyloarthritis. J Rheumatol. 2010;37:2606–16. - PubMed

[7] Mielants H, Veys EM, Cuvelier C, De Vos M, Botelberghe L. HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol. 1985;12:294–8. - PubMed

[8] Mielants H, Veys EM, Cuvelier C, De Vos M, Botelberghe L. HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol. 1985;12:294–8. - PubMed

[9] Friswell M, Campbell B, Rhodes J. The role of bacteria in the pathogenesis of inflammatory bowel disease. Gut and liver. 2010;4:295–306. - PMC - PubMed

[10] Friswell M, Campbell B, Rhodes J. The role of bacteria in the pathogenesis of inflammatory bowel disease. Gut and liver. 2010;4:295–306. - PMC - PubMed

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Time for a gut check: evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome

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Time for a gut check: evidence for the hypothesis that HLA-B27 predisposes to ankylosing spondylitis by altering the microbiome

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