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Review
. 2011 Jan-Feb;7(1):68-71.
doi: 10.1016/j.reuma.2009.09.010. Epub 2009 Dec 31.

[Citrullinated proteins in rheumatoid arthritis]

[Article in Spanish]
Elizabeth Olivares Martínez  1 , Diego F Hernández Ramírez, Carlos A Núñez-Álvarez, Javier Cabiedes
Affiliations
Free article
Review

[Citrullinated proteins in rheumatoid arthritis]

[Article in Spanish]
Elizabeth Olivares Martínez et al. Reumatol Clin. 2011 Jan-Feb.
Free article

Abstract

Rheumatoid arthritis is an autoimmune disease of multifactorial etiology characterized by inflammation of the joints and presence of autoantibodies directed against multiple autoantigens. Recently the study of the anti-citrullinated protein antibodies (ACP) has acquired great interest due to its high specificity and sensitivity for diagnosis, in addition to which it has shown to be a predictor of severity in patients with rheumatoid arthritis, suggesting an important participation in the pathogenesis of the disease.

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