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. 2011 Aug;17(8):1549-52.
doi: 10.3201/eid1708.101447.

Atypical pestivirus and severe respiratory disease in calves, Europe

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Atypical pestivirus and severe respiratory disease in calves, Europe

Nicola Decaro et al. Emerg Infect Dis. 2011 Aug.

Abstract

In 2010, a HoBi-like pestivirus was isolated from clinically affected calves in Italy. This European virus reproduced a milder form of disease under experimental conditions and was genetically related to previously reported HoBi-like strains. Isolation of this novel virus from a clinical outbreak may have implications for cattle health and prophylactic programs.

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Figures

Figure
Figure
Neighbor-joining unrooted trees based on the full-length genome (A), E2 (B), 5′ untranslated region (C), and Npro (D) sequences of members of the genus Pestivirus. For phylogenetic tree construction, pestivirus sequences listed in the Table were used. Asterisks indicate strong statistical support for a node by a bootstrap value of 75%–100%. Scale bars represent estimated numbers of nucleotide substitutions per site. CSFV, classical swine fever virus; BVDV-1, bovine viral diarrhea virus type 1; BVDV-2, bovine viral diarrhea virus type 2; BDV, border disease virus.

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