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. 2011 Dec;42(6):893-902.
doi: 10.1016/j.jpainsymman.2011.02.026. Epub 2011 Jul 30.

Aberrant behaviors with prescription opioids and problem drug use history in a community-based cohort of HIV-infected individuals

Luke Hansen  1 , Joanne Penko, David Guzman, David R Bangsberg, Christine Miaskowski, Margot B Kushel
Affiliations

Aberrant behaviors with prescription opioids and problem drug use history in a community-based cohort of HIV-infected individuals

Luke Hansen et al. J Pain Symptom Manage. 2011 Dec.

Abstract

Context: The treatment of pain in patients with substance use disorders creates tensions for clinicians between undertreating pain and enabling opioid analgesic misuse.

Objectives: To characterize prevalence and factors associated with aberrant opioid analgesic behaviors in a cohort of HIV-infected individuals who are at high risk for opioid analgesic misuse.

Methods: We assessed pain and substance use disorders in a cross-sectional study that enrolled 296 participants from the Research on Access to Care in the Homeless cohort, a community-based sample of indigent HIV-infected adults. We measured aberrant opioid behaviors, defined as major or minor depending on level of risk of harm to patients, using Audio Computer-Assisted Self-Interview technology.

Results: Most participants (91.2%) reported pain in the week before interview, with the majority of these experiencing severe pain (53.7%). More than two-thirds (69.2%) of the participants met criteria for a lifetime history of cocaine, amphetamine, or heroin/opioid use disorder as defined by the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition). More than one-third of the sample (37.4%) had a history of aberrant opioid behavior within 90 days of interview. One-fifth (18.5%) had a history of "major" aberrant behaviors.

Conclusion: In this high-risk population, severe pain is common and aberrant opioid behaviors are prevalent but not universal. As recommended by American Pain Society and American Academy of Pain Medicine guidelines, when prescribing opioid analgesics, clinicians must consider variation in the severity of aberrant behaviors, particularly aberrant behaviors that may represent undertreatment of pain.

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References

    1. Emergency Department Visits Involving Nonmedical Use of Selected Prescription Drugs---United States, 2004--2008. MMWE Morb Mortal Wkly Rep. 59(23):715–719. - PubMed
    1. Cai R, Crane E, Poneleit K, Paulozzi L. Emergency department visits involving nonmedical use of selected prescription drugs in the United States, 2004–2008. J Pain Palliat Care Pharmacother. 2010;24(3):293–297. - PubMed
    1. Gilson AM, Ryan KM, Joranson DE, Dahl JL. A reassessment of trends in the medical use and abuse of opioid analgesics and implications for diversion control: 1997–2002. J Pain Symptom Manage. 2004;28(2):176–188. - PubMed
    1. Chou R, Ballantyne JC, Fanciullo GJ, Fine PG, Miaskowski C. Research gaps on use of opioids for chronic noncancer pain: findings from a review of the evidence for an American Pain Society and American Academy of Pain Medicine Clinical Practice Guideline. J Pain. 2009;10(2):147–159. - PubMed
    1. Chou R, Fanciullo GJ, Fine PG, et al. American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel. Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain. J Pain. 2009;10(2):113–130. - PMC - PubMed

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