Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Jan;27(1):79-83.

Fospropofol: clinical pharmacology

Girish M Bengalorkar  1 , K Bhuvana, N Sarala, Tn Kumar
Affiliations

Fospropofol: clinical pharmacology

Girish M Bengalorkar et al. J Anaesthesiol Clin Pharmacol. 2011 Jan.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
2,6 diisopropyl phenol molecule (propofol) and prodrug variations
Figure 2
Figure 2
Metabolism of fospropofol into diisopropyl phenol (propofol), free phosphate, formaldehyde to formate
Annexure 1
Annexure 1
Modified Observer's Assessment of Alertness/ Sedation Scale
See this image and copyright information in PMC

References

    1. Garnock-Jones KP, Scott LJ. Fospropofol. Drugs. 2010;70(4):469–77. - PubMed
    1. Fanti L, Testoni PA. Sedation and analgesia in gastrointestinal endoscopy: What's new? World J Gastroenterol. 2010;16(20):2451–57. - PMC - PubMed
    1. Mueller SW, Moore GD, MacLaren R. Fospropofol Disodium for Procedural Sedation: Emerging Evidence of its Value? Clinical Medicine Insights: Therapeutics. 2010;2:513–22.
    1. Welliver M, Rugari SM. New drug, fospropofol disodium: a propofol prodrug. AANA J. 2009;77(4):301–8. - PubMed
    1. Fospropofol Disodium Injection NDA 22-244,MGI PHARMA, Inc. Briefing materials for the anaesthetic and life support drugs advisory committee to the division of anaesthesia, analgesia, and rheumatology products (DAARP)/CDER/FDA. 2008. May 7, [Accessed 2010 Aug 17]. Available from: http: www.fda.gov/ ohrms/dockets/ ac/08 /briefing/2008-4354b1-02-MGI.pdf.